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hypoxanthine biosynthetic process

Known as: hypoxanthine biosynthesis, hypoxanthine anabolism, hypoxanthine synthesis 
The chemical reactions and pathways resulting in the formation of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Structural and metabolic specificity of methylthiocoformycin for malarial adenosine deaminases.
Plasmodium falciparum is a purine auxotroph requiring hypoxanthine as a key metabolic precursor. Erythrocyte adenine nucleotides… Expand
2000
2000
Distinct Roles for Recombinant Cytosolic 5′-Nucleotidase-I and -II in AMP and IMP Catabolism in COS-7 and H9c2 Rat Myoblast Cell Lines*
Catabolism of AMP during ATP breakdown produces adenosine, which restores energy balance. Catabolism of IMP may be a key step… Expand
Highly Cited
1999
Highly Cited
1999
AMP deamination and purine exchange in human skeletal muscle during and after intense exercise
1 The present study examined the regulation of human skeletal muscle AMP deamination during intense exercise and quantified… Expand
1996
1996
Delay of adenosine triphosphate depletion and hypoxanthine formation in rabbit lung after death.
BACKGROUND If lungs could be retrieved for transplantation from non-heart-beating cadavers, the shortage of donors might be… Expand
1980
1980
Adenylate degradation in Escherichia coli. The role of AMP nucleosidase and properties of the purified enzyme.
Extracts of Escherichia coli K12 degrade AMP to hypoxanthine, adenine, adenosine, and inosine. Degradation experiments with… Expand
Highly Cited
1977
Highly Cited
1977
Metabolism and Function of Human Platelets Washed by Albumin Density Gradient Separation
A method for washing platelets by albumin density gradient separation, originally designed for the study of platelet coagulant… Expand
1975
1975
Metal ion contents of gel-filtered platelets from patients with storage pool disease.
Platelets from nine patients with storage pool disease (SPD) and from ten control subjects were isolated by gel filtration into a… Expand
1975
1975
The pathway of adenylate catabolism in Azotobacter vinelandii. Evidence for adenosine monophosphate nucleosidase as the regulatory enzyme.
Cell-free, dialyzed extracts from Azotobacter vinelandii rapidly dephosphorylate [U-14C]ATP to labeled ADP and AMP, which is then… Expand
1964
1964
PHOSPHATE, PURINES AND PYRIMIDINES AS EXCRETORY PRODUCTS OF TETRAHYMENA.
SYNOPSIS. Tetrahymena pyriformis strain W, incubated for 3 hours in a salts-PO4 medium, showed a net loss of phosphate from the… Expand
1953
1953
Biosynthesis of the purines. III. Reactions of formate and inosinic acid and an effect of the citrovorum factor.
Previous experiments have shown that when hypoxanthine is synthesized de novo from formate, glycine, and CO2 in extracts or… Expand
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