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hyaluronan biosynthetic process

Known as: hyaluronan formation, hyaluronan biosynthesis, hyaluronan anabolism 
The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of… 
National Institutes of Health

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negative regulation of hyaluronan biosynthetic processpositive regulation of hyaluronan biosynthetic processregulation of hyaluronan biosynthetic process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Hyperglycemia, intracellular hyaluronan synthesis, cyclin D3 and autophagy
Hyperglycemia is one of the factors that induces autophagy. Our recent studies demonstrate that dividing cells in hyperglycemic… 
Review
2007
Review
2007
Regulation of hyaluronan synthesis by vasodilatory prostaglandins
Summary Hyaluronan (HA) is a macromolecular polysaccharide of the vascular extracellular matrix that confers both structural… 
2004
2004
In Vivo Hyaluronan Synthesis upon Expression of the Mammalian Hyaluronan Synthase Gene in Drosophila*
Hyaluronan (HA) is a large linear polymer of repeating disaccharides of glucuronic acid and GlcNAc. Although HA is widely… 
Highly Cited
2002
Highly Cited
2002
Characterization of hyaluronan synthase expression and hyaluronan synthesis in bone marrow mesenchymal progenitor cells: predominant expression of HAS1 mRNA and up-regulated hyaluronan synthesis in…
Hyaluronan (HA) is suggested to play a role in the pathophysiology of multiple myeloma. To further investigate the role of HA in… 
2001
2001
Hyaluronan Digestion and Synthesis in an Experimental Model of Metastatic Tumour
To approach the question of hyaluronan catabolism in tumours, we have selected the cancer cell line H460M, a highly metastatic… 
2000
2000
Low-density lipoprotein stimulates mesangial cell proteoglycan and hyaluronan synthesis.
BACKGROUND Hyperlipidaemia leads to glomerulosclerosis in small mammals and may contribute to progressive renal disease in man… 
Highly Cited
1999
Highly Cited
1999
Synthesis and shedding of hyaluronan from plasma membranes of human fibroblasts and metastatic and non-metastatic melanoma cells.
The regulation of hyaluronan synthesis and shedding was analysed in human fibroblasts and in two melanoma cells that differed in… 
1994
1994
Effects of dibutyryl cyclic AMP on hyaluronan and proteoglycan synthesis by retroocular tissue fibroblasts in culture.
Deposition of glycosaminoglycan is one of the histological features of Graves' ophthalmopathy. Although retroocular tissue… 
Highly Cited
1990
Highly Cited
1990
TGF-beta enhances the production of hyaluronan in human lung but not in skin fibroblasts.
Review
1989
Review
1989
The role and regulation of tumour-associated hyaluronan.
Significantly increased levels of the glycosaminoglycan hyaluronan are often associated with human and animal tumours. In the… 
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