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holocyclotoxin

National Institutes of Health

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Broader (1)

Arthropod Venoms

Papers overview

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2018
2018
Transcriptome and toxin family analysis of the paralysis tick, Ixodes holocyclus.
The Australian paralysis tick (Ixodes holocyclus) secretes neuropathic toxins into saliva that induce host paralysis. Salivary… 
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2018
2018
Investigation of the efficacy of fluralaner spot-on (Bravecto®) against infestations of Ixodes holocyclus on cats
BackgroundInfestation of cats with the Australian paralysis tick, Ixodes holocyclus continues to be a threat because of the… 
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2016
2016
Tick holocyclotoxins trigger host paralysis by presynaptic inhibition
Ticks are important vectors of pathogens and secreted neurotoxins with approximately 69 out of 692 tick species having the… 
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2015
2015
A randomized controlled trial of the efficacy of orally administered fluralaner (Bravecto™) against induced Ixodes holocyclus (Australian paralysis tick) infestations on dogs
BackgroundIxodes holocyclus ticks are a frequently fatal threat to dogs in eastern Australia. These ticks secrete a neurotoxin… 
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2012
2012
Soft Ticks as Pathogen Vectors: Distribution, Surveillance and Control
Ticks are highly specialized obligate haematophagous ectoparasites of mammals, birds and reptiles. Ticks are distributed… 
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Review
2005
Review
2005
Tick/host interactions forIxodes holocyclus: Role, effects, biosynthesis and nature of its toxic and allergenic oral secretions
The Australian paralysis tickIxodes holocyclus occurs along the eastern coast of Australia. Its interaction with a wide variety… 
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1986
1986
Toxoid stimulation in dogs of high titres of neutralising antibodies against holocyclotoxin, the paralysing toxin of the Australian paralysis tick Ixodes holocyclus.
1983
1983
Tick (Ixodes holocyclus) paralysis in the dog--induction of immunity by injection of toxin.
Three beagle dogs were immunised against the paralysing effects of holocyclotoxin, using toxic extracts derived from salivary… 
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