heme biosynthetic process

Known as: haem biosynthetic process, heme anabolism, heme synthesis 
The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less… (More)
National Institutes of Health

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Highly Cited
2014
Highly Cited
2014
The thermal stability of proteins can be used to assess ligand binding in living cells. We have generalized this concept by… (More)
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Review
2008
Review
2008
Heme is an integral part of proteins involved in multiple electron transport chains for energy recovery found in almost all forms… (More)
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Highly Cited
2007
Highly Cited
2007
Genetic disorders of iron metabolism and chronic inflammation often evoke local iron accumulation. In Friedreich ataxia… (More)
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Highly Cited
2006
Highly Cited
2006
Iron has a fundamental role in many metabolic processes, including electron transport, deoxyribonucleotide synthesis, oxygen… (More)
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Highly Cited
2005
Highly Cited
2005
In most free-living eukaryotes studied thus far, heme is synthesized from a series of intermediates through a well defined… (More)
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Highly Cited
2005
Highly Cited
2005
Inducible hepatic porphyrias are inherited genetic disorders of enzymes of heme biosynthesis. The main clinical manifestations… (More)
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Review
2000
Review
2000
The heme biosynthetic and catabolic pathways generate pro- and antioxidant compounds, and consequently, influence cellular… (More)
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Review
1999
Review
1999
  • Prem Ponka
  • The American journal of the medical sciences
  • 1999
Heme is a complex of iron with protoporphyrin IX that is essential for the function of all aerobic cells. Heme serves as the… (More)
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Highly Cited
1998
Highly Cited
1998
Heme is a ubiquitous macromolecule that serves as the active group of proteins involved in many cellular processes. The… (More)
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Highly Cited
1996
Highly Cited
1996
One potential approach for characterizing uncultivated prokaryotes from natural assemblages involves genomic analysis of DNA… (More)
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