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harderoporphyrinogen

Known as: 21H,23H-Porphine-2,7,18-tripropanoic acid, 12-ethenyl-5,10,15,20,22,24-hexahydro-3,8,13,17-tetramethyl- 
National Institutes of Health

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Porphyrinogens

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2013
2013
The enzyme engineering of mutant homodimer and heterodimer of coproporphyinogen oxidase contributes to new insight into hereditary coproporphyria and harderoporphyria.
Hereditary coproporphyria (HCP) is an autosomal dominant-inherited disease of haem biosynthesis caused by partial deficiency of… 
2010
2010
The oxygen-independent coproporphyrinogen III oxidase HemN utilizes harderoporphyrinogen as a reaction intermediate during conversion of coproporphyrinogen III to protoporphyrinogen IX
Abstract During heme biosynthesis the oxygen-independent coproporphyrinogen III oxidase HemN catalyzes the oxidative… 
2010
2010
Normal and abnormal heme biosynthesis. 6. Synthesis and metabolism of a series of monovinylporphyrinogens related to harderoporphyrinogen. Further insights into the oxidative decarboxylation of…
A series of vinylporphyrinogens were prepared to probe the enzyme coproporphyrinogen oxidase (CPO). Six (2-chloroethyl)porphyrins… 
2006
2006
Investigation of the catalytic and structural roles of conserved histidines of human coproporphyrinogen oxidase using site-directed mutagenesis.
BACKGROUND The catalytic contribution of four conserved histidines of human coproporphyrinogen oxidase (CPO) has been… 
2005
2005
Metabolism of pentacarboxylate porphyrinogens by highly purified human coproporphyrinogen oxidase: further evidence for the existence of an abnormal pathway for heme biosynthesis.
2004
2004
Identification of monovinyl tripropionic acid porphyrins and metabolites from faeces of patients with hereditary coproporphyria by high-performance liquid chromatography/electrospray ionization…
Harderoporphyrin (2-vinyl-4,6,7-tripropionic acid porphyrin) and its metabolites in faeces of patients with hereditary… 
1978
1978
A radiochemical method for the measurement of coproporphyrinogen oxidase and the utilization of substrates other than coproporphyrinogen III by the enzyme from rat liver.
[14C2]Coproporphyrin III, 14C-labelled in the carboxyl carbon atoms of the 2- and 4-propionate substituents, was prepared by… 
1976
1976
Incubation of double labelled coproporphyrinogen with chicken red cell haemolysates, chemical and TLC fractionation of extracts.
Further evidence is presented for the enzymic conversion of protoporphyrinogen to protoporphyrin by observing the loss of 3H… 
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