guanine biosynthetic process

Known as: guanine anabolism, guanine biosynthesis, guanine synthesis 
The chemical reactions and pathways resulting in the formation of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found… Expand
National Institutes of Health

Papers overview

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2014
2014
Inhibition of Nucleotide Biosynthesis Potentiates the Antifungal Activity of Amphotericin B
The polyene antifungal agent Amphotericin B exhibits potent and broad spectrum fungicidal activity. However, high nephrotoxicity… Expand
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2008
2008
Flavonoid effects on DNA oxidation at low concentrations relevant to physiological levels.
Flavonoids, which are abundant in fruits and vegetables, are known to have many beneficial health effects. Antioxidant activity… Expand
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2007
2007
Dimemorfan protects rats against ischemic stroke through activation of sigma-1 receptor-mediated mechanisms by decreasing glutamate accumulation.
Dimemorfan, an antitussive and a sigma-1 (sigma(1)) receptor agonist, has been reported to display neuroprotective properties. We… Expand
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2006
2006
Formation of 06-Methylguanine by Alkylation of Rat Liver , Colon , and Kidney DNA following Administration of 1 , 2-Dimethylhydrazine 1
cinogen (3, 31). Tumors were also produced in the duo denum, small intestine, liver, and kidney by 1,2-dimethyl hydrazine (3, 10… Expand
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1999
1999
Molecular dosimetry of endogenous and ethylene oxide-induced N7-(2-hydroxyethyl) guanine formation in tissues of rodents.
The formation of N7-(2-hydroxyethyl)guanine (7-HEG) in DNA was investigated previously in target and non-target tissues of F-344… Expand
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1990
1990
Mediation of 8-hydroxy-guanine formation in DNA by thiazin dyes plus light.
We have discovered that methylene blue plus light mediates the formation of 8-OHdG in DNA. Methylene blue is one of several… Expand
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1989
1989
Inactivation of O6-alkylguanine-DNA alkyltransferase in HeLa cells by cisplatin.
Inactivation of O6-alkylguanine-DNA alkyltransferase (O6-AGT) in HeLa CCL2 cells by cisplatin was studied. HeLa CCL2 cells… Expand
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1976
1976
Specialized transduction of colicin E1 DNA in Escherichia coli K-12.
Genetic studies were made on E. coli K-12 TM96, which carries recombinant molecules constructed by in vitro combination of… Expand
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1960
1960
Inhibition of the biosynthesis of purines de novo by 6-chloropurine and azaserine in sensitive and naturally resistant ascites cells.
Abstract The action of 6-chloropurine and azaserine on the biosynthesis of guanine de novo was measured in five ascites-cell… Expand
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1960
1960
Modifications in purine metabolism induced by 6-chloropurine.
Abstract The effect of 6-chloropurine on the utilization of isotopic precursors of polynucleotide purines was investigated in… Expand
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