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growth differentiation factor 6

Known as: GDF-6, Growth Differentiation Factor 6 [Chemical/Ingredient] 
A growth differentiation factor that plays a role in the neural differentiation, specifically in the retinal development of the EYE.
National Institutes of Health

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GDF6 geneIn BloodProcess of secretionagonists
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GDF6B protein, zebrafishgdf6a protein, zebrafish

Papers overview

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2018
2018
Differentiation of MSC and annulus fibrosus cells on genetically engineered silk fleece‐membrane‐composites enriched for GDF‐6 or TGF‐&bgr;3
Intervertebral disc (IVD) repair is a high-priority topic in our active and increasingly ageing society. Since a high number of… Expand
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2016
2016
Expression of growth differentiation factor 6 in the human developing fetal spine retreats from vertebral ossifying regions and is restricted to cartilaginous tissues.
During embryogenesis vertebral segmentation is initiated by sclerotomal cell migration and condensation around the notochord… Expand
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2016
2016
Combined effects of engineered tendon matrix and GDF-6 on bone marrow mesenchymal stem cell-based tendon regeneration
ObjectivesTo examine whether an engineered tendon matrix (ETM) environment and growth and differentiation factor-6 (GDF-6) have… Expand
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2016
2016
Identification of GDF-6 blocking antibodies as anti-melanoma therapeutics
Identification of GDF-6 blocking antibodies as anti-melanoma therapeutics" 
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2013
2013
Effect of growth and differentiation factor 6 on the tenogenic differentiation of bone marrow-derived mesenchymal stem cells.
BACKGROUND Recent studies showed that bone marrow-derived mesenchymal stem cells (BMSCs) had risk of ectopic bone formation. In… Expand
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2009
2009
Sexual dimorphism in the effect of GDF-6 deficiency on murine tendon.
Three members of the growth/differentiation factor (GDF) subfamily of bone morphogenetic proteins (BMPs), GDFs-5, -6, and -7… Expand
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2006
2006
Achilles tendon characterization in GDF-7 deficient mice.
Growth/differentiation factors (GDFs) play a significant role in numerous skeletal tissues and processes. Previous work using the… Expand
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Highly Cited
2002
Highly Cited
2002
Osteogenic protein‐1 (OP‐1, BMP‐7) induces osteoblastic cell differentiation of the pluripotent mesenchymal cell line C2C12
The effects of Osteogenic Protein‐1 (OP‐1, BMP‐7) on the differentiation of the pluripotent mesenchymal cell line, C2C12, were… Expand
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Highly Cited
1999
Highly Cited
1999
Different effects of bone morphogenetic proteins 2, 4, 12, and 13 on the expression of cartilage and bone markers in the MC615 chondrocyte cell line.
In order to study the lineage leading to chondrocyte and osteoblast phenotype in vertebrate development, we examined the effect… Expand
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1994
1994
Facteur 6 de croissance et de differenciation cellulaires
Facteur 6 de croissance et de differenciation cellulaires (GDF-6), ainsi que sa sequence nucleotidique et sa sequence d'acides… Expand
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