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granulin 4

Known as: epithelin-1, CS5931, granulin A 
National Institutes of Health

Papers overview

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2011
2011
Granulin-Epithelin Precursor Is an Oncofetal Protein Defining Hepatic Cancer Stem Cells
Background and Aims Increasing evidence has suggested that hepatocellular carcinoma (HCC) might originate from a distinct… 
Highly Cited
2010
Highly Cited
2010
Granulin epithelin precursor: a bone morphogenic protein 2‐inducible growth factor that activates Erk1/2 signaling and JunB transcription factor in chondrogenesis
Granulin epithelin precursor (GEP) has been implicated in development, tissue regeneration, tumorigenesis, and inflammation… 
Highly Cited
2010
Highly Cited
2010
Expression of Progranulin (Acrogranin/PCDGF/Granulin-Epithelin Precursor) in Benign and Malignant Ovarian Tumors and Activation of MAPK Signaling in Ovarian Cancer Cell Line
ABSTRACT It has been recently demonstrated that progranulin is overexpressed in ovarian cancer and that this protein is involved… 
Highly Cited
2007
Highly Cited
2007
Prosurvival function of the granulin‐epithelin precursor is important in tumor progression and chemoresponse
The granulin‐epithelin precursor (GEP/PCDGF), a 68–88 kDa secreted glycoprotein, has been shown to be an important growth and… 
Highly Cited
2005
Highly Cited
2005
Lysophosphatidic acid and endothelin-induced proliferation of ovarian cancer cell lines is mitigated by neutralization of granulin–epithelin precursor (GEP), a prosurvival factor for ovarian cancer
Granulin-epithelin precursor (GEP/progranulin) is an autocrine growth factor for ovarian cancer. We examined the production and… 
Highly Cited
2004
Highly Cited
2004
Granulin–Epithelin Precursor Overexpression Promotes Growth and Invasion of Hepatocellular Carcinoma
Purpose: Granulin–epithelin precursor (GEP) is a novel growth factor. Our earlier cDNA microarray study indicated that GEP was… 
Review
2003
Review
2003
The granulin-epithelin precursor: a putative new growth factor for ovarian cancer.
Highly Cited
1998
Highly Cited
1998
Identification of a sex steroid-inducible gene in the neonatal rat hypothalamus
1993
1993
Biochemical analysis of the epithelin receptor.
Highly Cited
1990
Highly Cited
1990
Epithelins 1 and 2: isolation and characterization of two cysteine-rich growth-modulating proteins.
Two proteins, termed epithelin 1 and epithelin 2, that inhibit the growth of A431 cells, derived from a human epidermal carcinoma… 
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