glycosylase
National Institutes of Health
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Oxidative base damage occurs spontaneously due to reactive oxygen species generated as byproducts of respiration and other…
Human alkyladenine-DNA glycosylase (AAG) initiates base excision repair (BER) of alkylated and deaminated bases in DNA. Here, we…
Reactive oxygen species induce a pharmacopoeia of oxidized bases in DNA. DNA can be cleaved at most of the sites of these…