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glycosaminoglycan catabolism

Known as: glycosaminoglycan breakdown, glycosaminoglycan catabolic process, glycosaminoglycan degradation 
The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars… Expand
National Institutes of Health

Papers overview

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2015
2015
Peroxisome proliferator-activated receptor δ promotes the progression of posttraumatic osteoarthritis in a mouse model.
OBJECTIVE Osteoarthritis (OA) is a serious disease of the entire joint, characterized by articular cartilage degeneration… Expand
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Highly Cited
2012
Highly Cited
2012
Metabolic Reconstruction for Metagenomic Data and Its Application to the Human Microbiome
Microbial communities carry out the majority of the biochemical activity on the planet, and they play integral roles in processes… Expand
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Highly Cited
2008
Highly Cited
2008
Lactic acid bacteria inhibit proinflammatory cytokine expression and bacterial glycosaminoglycan degradation activity in dextran sulfate sodium-induced colitic mice.
To evaluate the effect of lactic acid bacteria (LAB) in inflammatory bowel diseases (IBD), inhibitory effect of several LAB… Expand
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Highly Cited
2004
Highly Cited
2004
Fibroblast invasive migration into fibronectin/fibrin gels requires a previously uncharacterized dermatan sulfate-CD44 proteoglycan.
After tissue injury, fibroblast migration from the peri-wound collagenous stroma into the fibrin-laden wound is critical for… Expand
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Highly Cited
2001
Highly Cited
2001
Effect of glycosaminoglycan degradation on lung tissue viscoelasticity.
We tested the hypothesis that matrix glycosaminoglycans contribute to lung tissue viscoelasticity. We exposed lung parenchymal… Expand
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Highly Cited
1999
Highly Cited
1999
Inhibition of lysosomal degradative functions in RPE cells by a retinoid component of lipofuscin.
PURPOSE To investigate the effect of the lipofuscin component N-retinylidene-N-retinylethanolamine (A2-E) on degradative… Expand
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1990
1990
Polysulfated glycosaminoglycan accelerates net synthesis of collagen and glycosaminoglycans by arthritic equine cartilage tissues and chondrocytes.
Low molecular weight polysulfated glycosaminoglycan (PSGAG) stimulated net collagen and glycosaminoglycan synthesis by normal and… Expand
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1984
1984
Dexamethasone regulation of glycosaminoglycan synthesis in cultured human skin fibroblasts. Similar effects of glucocorticoid and thyroid hormones.
The effects of dexamethasone on glycosaminoglycan accumulation were examined in confluent human skin fibroblasts in vitro. The… Expand
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Highly Cited
1979
Highly Cited
1979
Collagen reduces glycosaminoglycan degradation by cultured mammary epithelial cells: possible mechanism for basal lamina formation.
Collagenous substrates are reported to promote the accumulation of extracellular matrix materials by epithelia in culture… Expand
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1977
1977
Mucopolysaccharidosis in a cat with arylsulfatase B deficiency: a model of Maroteaux-Lamy syndrome
A Siamese cat that presented clinical signs similar to those seen in humans with mucopolysaccharidoses was studied. The animal… Expand
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