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glycosaminoglycan catabolism

Known as: glycosaminoglycan breakdown, glycosaminoglycan catabolic process, glycosaminoglycan degradation 
The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars… 
National Institutes of Health

Papers overview

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Highly Cited
2019
Highly Cited
2019
Metagenome-wide association study of gut microbiome revealed novel aetiology of rheumatoid arthritis in the Japanese population
Objective The causality and pathogenic mechanism of microbiome composition remain elusive in many diseases, including autoimmune… 
Highly Cited
2008
Highly Cited
2008
Lactic acid bacteria inhibit proinflammatory cytokine expression and bacterial glycosaminoglycan degradation activity in dextran sulfate sodium-induced colitic mice.
2007
2007
A Role for Proteoglycans in Mineralized Tissue-Titanium Adhesion
Biomechanical properties of the bone-titanium interface have rarely been studied, due to the technical limitations involved… 
Highly Cited
2004
Highly Cited
2004
Fibroblast invasive migration into fibronectin/fibrin gels requires a previously uncharacterized dermatan sulfate-CD44 proteoglycan.
After tissue injury, fibroblast migration from the peri-wound collagenous stroma into the fibrin-laden wound is critical for… 
Highly Cited
2001
Highly Cited
2001
Effect of glycosaminoglycan degradation on lung tissue viscoelasticity.
We tested the hypothesis that matrix glycosaminoglycans contribute to lung tissue viscoelasticity. We exposed lung parenchymal… 
Highly Cited
1984
Highly Cited
1984
Dexamethasone regulation of glycosaminoglycan synthesis in cultured human skin fibroblasts. Similar effects of glucocorticoid and thyroid hormones.
The effects of dexamethasone on glycosaminoglycan accumulation were examined in confluent human skin fibroblasts in vitro. The… 
Review
1984
Review
1984
Enzymatic adaptation in ligaments during immobilization
Ligaments are a composite of fibroblasts and collagen in a proteoglycan matrix. Seventy-five percent of the organic solid is… 
Highly Cited
1979
Highly Cited
1979
Collagen reduces glycosaminoglycan degradation by cultured mammary epithelial cells: possible mechanism for basal lamina formation.
Collagenous substrates are reported to promote the accumulation of extracellular matrix materials by epithelia in culture… 
Highly Cited
1977
Highly Cited
1977
Mucopolysaccharidosis in a cat with arylsulfatase B deficiency: a model of Maroteaux-Lamy syndrome
A Siamese cat that presented clinical signs similar to those seen in humans with mucopolysaccharidoses was studied. The animal… 
Highly Cited
1974
Highly Cited
1974
Sandhoff disease: defective glycosaminoglycan catabolism in cultured fibroblasts and its correction by beta-N-acetylhexosaminidase.
1. Fibroblasts cultured from the skin of patients with Sandhoff disease accumulate excessive amounts of sulfated… 
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