Skip to search formSkip to main contentSkip to account menu

glycine receptor, alpha4-subunit

Known as: GlyR alpha4 subunit, glycine receptor alpha-4 subunit 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Glycine Receptors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
The intracellular domain of homomeric glycine receptors modulates agonist efficacy.
Like other pentameric ligand-gated channels, glycine receptors (GlyRs) contain long intracellular domains (ICDs) between… 
2017
2017
The Discovery and Hit-to-Lead Optimization of Tricyclic Sulfonamides as Potent and Efficacious Potentiators of Glycine Receptors.
Current pain therapeutics suffer from undesirable psychotropic and sedative side effects, as well as abuse potential. Glycine… 
2011
2011
A Single Phenylalanine Residue in the Main Intracellular Loop of &agr;1 &ggr;-Aminobutyric Acid Type A and Glycine Receptors Influences Their Sensitivity to Propofol
Background: The intravenous anesthetic propofol acts as a positive allosteric modulator of glycine (GlyRs) and &ggr;-aminobutyric… 
2011
2011
A Cation-π Interaction at a Phenylalanine Residue in the Glycine Receptor Binding Site Is Conserved for Different Agonists
Cation-π interactions have been demonstrated to play a major role in agonist-binding in Cys-loop receptors. However, neither the… 
2011
2011
The trafficking proteins Vacuolar Protein Sorting 35 and Neurobeachin interact with the glycine receptor β-subunit.
2006
2006
Molecular determinants of ginkgolide binding in the glycine receptor pore
Ginkgolides are potent blockers of the glycine receptor Cl– channel (GlyR) pore. We sought to identify their binding sites by… 
2006
2006
Mechanisms for picrotoxin block of alpha2 homomeric glycine receptors.
It is well known that the convulsant alkaloid picrotoxin (PTX) can inhibit neuronal gamma-aminobutyric acid (GABA) and homomeric… 
2005
2005
RNA editing produces glycine receptor alpha3(P185L), resulting in high agonist potency.
The function of supramedullary glycine receptors (GlyRs) is still unclear. Using Wistar rat collicular slices, we demonstrate… 
Highly Cited
2004
Highly Cited
2004
GlyR α3: An Essential Target for Spinal PGE2-Mediated Inflammatory Pain Sensitization
Prostaglandin E2 (PGE2) is a crucial mediator of inflammatory pain sensitization. Here, we demonstrate that inhibition of a… 
2002
2002
The General Anesthetic Pentobarbital Slows Desensitization and Deactivation of the Glycine Receptor in the Rat Spinal Dorsal Horn Neurons*
Although many general anesthetics have been found to produce anesthetic and analgesic effects by augmenting GABAA receptor… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)