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glycine N-methyltransferase activity

Known as: S-adenosyl-L-methionine:glycine methyltransferase activity, glycine methyltransferase activity, GNMT 
Catalysis of the reaction: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine. [EC:2.1.1.20]
National Institutes of Health

Papers overview

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2018
2018
The origin of enzyme catalysis remains a question of debate despite much intense study. We report a QM/MM theoretical study of… Expand
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2016
2016
Glycine N-methyltransferase (GNMT) expression is vastly downregulated in hepatocellular carcinomas (HCC). High rates of GNMT… Expand
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2009
2009
UNLABELLED Hepatic S-adenosylmethionine (SAMe) is maintained constant by the action of methionine adenosyltransferase I/III (MATI… Expand
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Highly Cited
2008
Highly Cited
2008
UNLABELLED Glycine N-methyltransferase (GNMT) is the main enzyme responsible for catabolism of excess hepatic S… Expand
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2008
2008
BACKGROUND AND AIM Glycine N-methyltransferase (GNMT) is a susceptibility gene for human hepatocellular carcinoma (HCC). We… Expand
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2008
2008
SAMe (S-adenosylmethionine) is the main methyl donor group in the cell. MAT (methionine adenosyltransferase) is the unique enzyme… Expand
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Highly Cited
2006
Highly Cited
2006
Three human cases having mutations in the glycine N-methyltransferase (GNMT) gene have been reported. This enzyme transfers a… Expand
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Highly Cited
2004
Highly Cited
2004
Glycine N-methyltransferase (GNMT) affects genetic stability by (a) regulating the ratio of S-adenosylmethionine to S… Expand
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Highly Cited
2002
Highly Cited
2002
Glycine N-methyltransferase (GNMT) regulates S-adenosylmethionine (SAM) levels and the ratio of SAM:S-adenosylhomocysteine (SAH… Expand
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Highly Cited
1994
Highly Cited
1994
Glycine N-methyltransferase (GNMT; S-adenosyl-L-methionine:glycine N-methyltransferase, EC 2.1.1.20) is a major protein in rat… Expand
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