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glycine N-methyltransferase activity
Known as:
S-adenosyl-L-methionine:glycine methyltransferase activity
, glycine methyltransferase activity
, GNMT
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Catalysis of the reaction: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine. [EC:2.1.1.20]
National Institutes of Health
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Related topics
Related topics
1 relation
GNMT gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Characterization of the GNMT‐HectH9‐PREX2 tripartite relationship in the pathogenesis of hepatocellular carcinoma
Chung-Hsien Li
,
Chia-Hung Yen
,
+7 authors
Yi-Ming Arthur Chen
International Journal of Cancer
2017
Corpus ID: 41809861
The pathogenesis of hepatocellular carcinoma (HCC) involves many molecular pathways. Glycine N‐methyltransferase (GNMT) is…
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2015
2015
Regulation of Folate-Mediated One-Carbon Metabolism by Glycine N-Methyltransferase (GNMT) and Methylenetetrahydrofolate Reductase (MTHFR).
Yi‐Cheng Wang
,
Ming-Tsung Wu
,
Yan‐Jun Lin
,
Feng-Yao Tang
,
Hsin‐An Ko
,
E. Chiang
Journal of Nutritional Science and Vitaminology
2015
Corpus ID: 10598761
Folate-mediated one-carbon metabolism is an important therapeutic target of human diseases. We extensively investigated how gene…
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Review
2013
Review
2013
The multi-functional roles of GNMT in toxicology and cancer.
Chia-Hung Yen
,
Yu-Ting Lin
,
Heng-Li Chen
,
Shih-Yin Chen
,
Y. Chen
Toxicology and Applied Pharmacology
2013
Corpus ID: 46651213
2010
2010
Benzo(a)pyrene induced glycine N-methyltransferase messenger RNA expression in Fundulus heteroclitus embryos.
X. Fang
,
Wu Dong
,
C. Thornton
,
B. Scheffler
,
K. Willett
Marine Environmental Research
2010
Corpus ID: 6531977
2008
2008
Methyltetrahydrofolate in folate-binding protein glycine N-methyltransferase.
Z. Luka
Vitamins and hormones
2008
Corpus ID: 9880884
2003
2003
Biochemical and Molecular Actions of Nutrients All-trans-Retinoic Acid Rapidly Induces Glycine N-methyltransferase in a Dose-Dependent Manner and Reduces Circulating Methionine and Homocysteine…
Marlies K. Ozias
,
K. Schalinske
2003
Corpus ID: 4493790
Glycine N-methyltransferase (GNMT) regulates the methyl group supply for S-adenosylmethionine– dependent transmethylation…
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2003
2003
Expression and purification of glycine N-methyltransferases in Escherichia coli.
Z. Luka
,
C. Wagner
Protein Expression and Purification
2003
Corpus ID: 38188761
1997
1997
Glycine N-Methyltransferase Is an Example of Functional Diversity
R. Bhat
,
E. Bresnick
Journal of Biological Chemistry
1997
Corpus ID: 31679332
The cytochrome P-4501A1 (CYP1A1) gene is regulated by several trans-acting factors including the 4 S polycyclic aromatic…
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Highly Cited
1989
Highly Cited
1989
Effect of dietary methyl group deficiency on one-carbon metabolism in rats.
R. Cook
,
D. W. Horne
,
C. Wagner
Journal of NutriLife
1989
Corpus ID: 4452633
Amino acid-defined diets deficient in methyl groups have been shown to result in a very high incidence of hepatocellular…
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1982
1982
Induction of rat liver glycine methyltransferase by high methionine diet.
H. Ogawa
,
M. Fujioka
Biochemical and Biophysical Research…
1982
Corpus ID: 9574075
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