glycine N-methyltransferase activity

Known as: S-adenosyl-L-methionine:glycine methyltransferase activity, glycine methyltransferase activity, GNMT 
Catalysis of the reaction: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine. [EC:2.1.1.20]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2018
051019752018

Papers overview

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2016
2016
Glycine N-methyltransferase (GNMT) expression is vastly downregulated in hepatocellular carcinomas (HCC). High rates of GNMT… (More)
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2013
2013
Androgen plays an important role in the pathogenesis of PCa (prostate cancer). Previously, we identified GNMT (glycine N… (More)
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2011
2011
Glycine N-methyltransferase (GNMT) is a major hepatic enzyme that converts S-adenosylmethionine to S-adenosylhomocysteine while… (More)
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2009
2009
UNLABELLED Hepatic S-adenosylmethionine (SAMe) is maintained constant by the action of methionine adenosyltransferase I/III (MATI… (More)
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2009
2009
Previously, we reported that glycine N-methyltransferase (GNMT) knockout mice develop chronic hepatitis and hepatocellular… (More)
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2009
2009
Previous studies showed that S-Adenosylmethionine (SAMe) prevented MDB formation and the hypomethylation of histones induced by… (More)
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2008
2008
SAMe (S-adenosylmethionine) is the main methyl donor group in the cell. MAT (methionine adenosyltransferase) is the unique enzyme… (More)
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2005
2005
Glycine N-methyltransferase (GNMT) is a key regulatory protein in folate metabolism, methionine availability, and… (More)
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2003
2003
Glycine N-methyltransferase (GNMT), a multifunctional protein involved in the maintenance of the genetic stability, is often down… (More)
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2000
2000
Glycine N-methyltransferase (S-adenosyl-l-methionine: glycine methyltransferase, EC 2.1.1.20; GNMT) catalyzes the AdoMet… (More)
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