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glyceryl 1,2-dinitrate

Known as: Glycerol, 1,2-Dinitrate, propanetriol 1,2-dinitrate, 1,2-dinitroglycerol 
National Institutes of Health

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Broader (1)

dinitroglycerol

Papers overview

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2006
2006
Simultaneous determination of nitroglycerin and dinitrate metabolites in metabolism studies using liquid chromatography-mass spectrometry with electrospray ionization.
1995
1995
Comparative Pharmacokinetics and Bioavailability of Nitroglycerin and its Metabolites from Transderm‐Nitro, Nitrodisc, and Nitro‐Dur II Systems Using a Stable‐Isotope Technique
The pharmacokinetics and bioavailability of nitroglycerin (GTN) and its metabolites, 1,2‐glyceryl dinitrate (1,2‐GDN) and 1,3… 
1994
1994
Bioequivalence evaluation of the metabolites 1,2 and 1,3-glyceryl dinitrate of two different glyceryl trinitrate patches after 12-h usage in healthy volunteers.
In the course of this study both the bioavailability and main pharmacokinetic parameters of the glyceryl trinitrate (GTN, CAS 55… 
1994
1994
The effects of hypothermic and normothermic cardiopulmonary bypass on glyceryl trinitrate activity.
Glyceryl trinitrate (GTN) is used to control arterial blood pressure during cardiopulmonary bypass (CPB) procedures, but its… 
1993
1993
Effect of temperature on glyceryl trinitrate induced relaxation of rabbit aorta.
It has previously been shown that the vasodilatory response to glyceryl trinitrate (GTN) was decreased during hypothermic… 
1992
1992
Comparison of vasodilatory responses to nitroglycerin and its dinitrate metabolites in human veins
Independent of the route of nitroglycerin administration, substantial amounts of 1,2‐glyceryl dinitrate (1,2‐GDN) and 1,3… 
1992
1992
Cutaneous Metabolism of Nitroglycerin in Vitro. II. Effects of Skin Condition and Penetration Enhancement
The effects of skin storage, skin preparation, skin pretreatment with a penetration enhancer, and skin barrier removal by… 
1990
1990
Assay of glyceryl trinitrate, isosorbide dinitrate, and their metabolites in plasma by large‐bore capillary column gas‐liquid chromatography
Two large‐bore capillary columns, one with dimethyl polysiloxane (HP‐1®) as the stationary phase and the other with phenyl (50… 
1989
1989
Differential biotransformation of glyceryl trinitrate by red blood cell-supernatant fraction and pulmonary vein homogenate.
We have demonstrated previously that glyceryl trinitrate (GTN) undergoes biotransformation to two glyceryl dinitrate (GDN… 
1988
1988
Patterns of isosorbide dinitrate and glyceryl trinitrate metabolites formed by selected segments of the rabbit gastrointestinal tract.
Homogenates of selected segments of the rabbit gastrointestinal tract (GIT) were studied for their ability to biotransform… 
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