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glyceryl 1,2-dinitrate

Known as: Glycerol, 1,2-Dinitrate, propanetriol 1,2-dinitrate, 1,2-dinitroglycerol 
National Institutes of Health

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dinitroglycerol

Papers overview

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2006
2006
Simultaneous determination of nitroglycerin and dinitrate metabolites in metabolism studies using liquid chromatography-mass spectrometry with electrospray ionization.
Review
2002
Review
2002
After 130 years, the molecular mechanism of action of nitroglycerin is revealed
Nitroglycerin, which was originally synthesized by Ascanio Sobrero, was used by Alfred Nobel to manufacture dynamite. It was in… 
2000
2000
Bioavailability and Pharmacokinetic Profile of Glyceryl Trinitrate and of Glyceryl Dinitrates during Application of a New Glyceryl Trinitrate Transdermal Patch
Summary The pharmacokinetics and bioavailability of glyceryl trinitrate (GTN, CAS 55-63-0) and of its main metabolites, i.e. 1,2… 
2000
2000
Plasma Levels of Glyceryl Trinitrate and Dinitrates during Application of Three Strengths of a New Glyceryl Trinitrate Transdermal Patch
Summary The pharmacokinetic characteristics and the bioavailability of glyceryl trinitrate (GTN, CAS 55-63-0) and of its main… 
1994
1994
Bioequivalence evaluation of the metabolites 1,2 and 1,3-glyceryl dinitrate of two different glyceryl trinitrate patches after 12-h usage in healthy volunteers.
In the course of this study both the bioavailability and main pharmacokinetic parameters of the glyceryl trinitrate (GTN, CAS 55… 
1990
1990
Pharmacokinetics of nitroglycerin and its dinitrate metabolites over a thirtyfold range of oral doses
The pharmacokinetics of nitroglycerin and the formation of its dinitrate metabolites (1,2‐glyceryl dinitrate and 1,3‐glyceryl… 
1990
1990
Formation of glyceryl 2‐mononitrate by regioselective bioconversion of glyceryl trinitrate: efficiency of the filamentous fungus Phanerochaete chrysosporium
Various microorganisms have been evaluated for their ability to hydrolyze glyceryl trinitrate (GTN) to glyceryl dinitrates and… 
1990
1990
Assay of glyceryl trinitrate, isosorbide dinitrate, and their metabolites in plasma by large‐bore capillary column gas‐liquid chromatography
Two large‐bore capillary columns, one with dimethyl polysiloxane (HP‐1®) as the stationary phase and the other with phenyl (50… 
1989
1989
Differential biotransformation of glyceryl trinitrate by red blood cell-supernatant fraction and pulmonary vein homogenate.
We have demonstrated previously that glyceryl trinitrate (GTN) undergoes biotransformation to two glyceryl dinitrate (GDN… 
1987
1987
Variable glyceryl dinitrate formation as a function of route of nitroglycerin administration
Plasma concentrations of 1,2‐ and 1,3‐glyceryl dinitrates were measured in each of four healthy volunteers who received… 
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