glutathione peroxidase activity

Known as: selenium-glutathione peroxidase activity, reduced glutathione peroxidase activity, GSH peroxidase activity 
Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O. [EC:1.11.1.9]
National Institutes of Health

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negative regulation of glutathione peroxidase activitypositive regulation of glutathione peroxidase activity

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Highly Cited
2008
Highly Cited
2008
Reduced selenium concentrations and glutathione peroxidase activity in preeclamptic pregnancies.
Preeclampsia is pregnancy-specific, affecting 2% to 7% of women, and is a leading cause of perinatal and maternal morbidity and… (More)
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Highly Cited
2007
Highly Cited
2007
DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase.
Parkinson's disease (PD) is a common neurodegenerative movement disorder. Whereas the majority of PD cases are sporadic, rare… (More)
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2002
2002
Erythrocyte glutathione peroxidase activity, plasma malondialdehyde and erythrocyte glutathione levels in hemodialysis and CAPD patients.
OBJECTIVES Cardiovascular disease is the major cause of mortality in patients receiving hemodialysis (HD) and continuous… (More)
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Highly Cited
2000
Highly Cited
2000
Stress tolerance in transgenic tobacco seedlings that overexpress glutathione S-transferase/glutathione peroxidase.
Overexpression of a tobacco glutathione S-transferase with glutathione peroxidase activity (GST/GPX) in transgenic tobacco… (More)
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Highly Cited
1997
Highly Cited
1997
Zeta, a novel class of glutathione transferases in a range of species from plants to humans.
Sequence alignment and phylogenetic analysis has identified a new subgroup of glutathione S-transferase (GST)-like proteins from… (More)
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Highly Cited
1996
Highly Cited
1996
Elevation in the ratio of Cu/Zn-superoxide dismutase to glutathione peroxidase activity induces features of cellular senescence and this effect is mediated by hydrogen peroxide.
Although reactive oxygen species have been proposed to play a major role in the aging process, the exact molecular mechanisms… (More)
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Highly Cited
1991
Highly Cited
1991
Selenium metabolism and platelet glutathione peroxidase activity in healthy Finnish men: effects of selenium yeast, selenite, and selenate.
The mean dietary selenium intake in Finland increased from 40 to 100 micrograms/d in 1987 because of the addition in 1985 of… (More)
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1989
1989
Blood selenium concentrations and glutathione peroxidase activity.
Selenium concentrations in children and teenagers without a metabolic disorder eating normal diets (group 1), and young patients… (More)
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1988
1988
Erythrocyte glutathione peroxidase activity in asthmatic children.
Erythrocyte glutathione peroxidase (GPX) levels were determined in 56 asthmatic children. Lowest levels were found during acute… (More)
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Highly Cited
1985
Highly Cited
1985
Effects of cadmium on glutathione peroxidase, superoxide dismutase, and lipid peroxidation in the rat heart: a possible mechanism of cadmium cardiotoxicity.
Cadmium treatment of rats maintained on a low-selenium diet produced a significant increase in specific heart weight together… (More)
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