glutaminyl-peptide cyclotransferase

Known as: EC 2.3.2.5, Glutaminyl-tRNA Cyclotransferase, sQC 
Glutaminyl-peptide cyclotransferase (361 aa, ~41 kDa) is encoded by the human QPCT gene. This protein is involved in the synthesis of cyclic glutamyl… (More)
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
MOTIVATION Fast and accurate quality control is essential for studies involving next-generation sequencing data. Whilst numerous… (More)
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Review
2014
Review
2014
Treatment of Alzheimer's disease (AD) is significantly hampered by the lack of easily accessible biomarkers that can detect… (More)
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Highly Cited
2012
Highly Cited
2012
Extracellular plaques of amyloid-b and intraneuronal neurofibrillary tangles made from tau are the histopathological signatures… (More)
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Highly Cited
2011
Highly Cited
2011
In recent years, procedures for selecting the N-terminal peptides of proteins with analysis by mass spectrometry have been… (More)
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Highly Cited
2008
Highly Cited
2008
Because of their abundance, resistance to proteolysis, rapid aggregation and neurotoxicity, N-terminally truncated and, in… (More)
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Highly Cited
2005
Highly Cited
2005
A substantial amount of theoretical work predicts that quality plays an important role as a determinant of the global patterns of… (More)
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Highly Cited
2004
Highly Cited
2004
N-terminal pyroglutamate (pGlu) formation from glutaminyl precursors is a posttranslational event in the processing of bioactive… (More)
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Highly Cited
1994
Highly Cited
1994
BACKGROUND Orthostatic syncope is usually attributed to cerebral hypoperfusion secondary to systemic hemodynamic collapse. Recent… (More)
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Highly Cited
1991
Highly Cited
1991
A glutaminyl cyclase (QC) that is probably involved in the biosynthesis of pyroglutamyl peptides such as gonadotropin-releasing… (More)
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Highly Cited
1987
Highly Cited
1987
Extracts from bovine pituitary were found to contain an activity catalyzing the conversion of glutaminyl peptides such as [Gln1… (More)
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