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glucosylceramide biosynthetic process

Known as: glucosylceramide biosynthesis, glucosylceramide anabolism, glucosylceramide synthesis 
The chemical reactions and pathways resulting in the formation of glucosylceramides, any compound formed by the replacement of the glycosidic… 
National Institutes of Health

Papers overview

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2003
2003
The absence of functional glucosylceramide synthase does not sensitize melanoma cells for anticancer drugs
Conversion of ceramide, a putative mediator of anticancer drug‐induced apoptosis, into glucosylceramide, by the action of… 
2002
2002
Inhibition of the sterol pathway in leek seedlings impairs phosphatidylserine and glucosylceramide synthesis but triggers an accumulation of triacylglycerols.
2001
2001
Glucosylceramide Synthesis Inhibitors Block Pharmacologically Induced Dispersal of the Golgi and Anterograde Membrane Flow from the Endoplasmic Reticulum: Implication of Sphingolipid Metabolism in…
PDMP (D,L-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol) and PPMP (D,L-threo-1-phenyl-2-hexadecanoylamino-3-morpholino-1… 
2000
2000
Compartmentation and topology of glucosylceramide synthesis.
Evidence is presented supporting a model for glucosylceramide formation on the apoplastic side of the plasma membrane in plants… 
2000
2000
Use in the treatment of glucosylceramide synthesis inhibitors
(57) Abstract: The present invention, Niemann - Pick C storage disease, Alzheimer's disease, epilepsy, seizures, treatment of… 
2000
2000
The combination of glucosylceramide synthesis inhibitors and glycolipid degrading enzymes in the treatment
(57) Abstract: The present invention is in the manufacture of a medicament for the treatment of diseases that have an element… 
1999
1999
Ceramide toxicity and metabolism differ in wild-type and multidrug-resistant cancer cells.
Previously we demonstrated that multidrug-resistant (MDR) cancer cells have elevated levels of a glycosylated form of ceramide… 
1997
1997
Ceramide glucosylation in bean hypocotyl microsomes: evidence that steryl glucoside serves as glucose donor.
The formation of glucosylceramide, the predominant sphingolipid in plant tissues, was examined in microsomes from wax bean… 
Highly Cited
1996
Highly Cited
1996
Oxidized low density lipoprotein stimulates aortic smooth muscle cell proliferation.
We have investigated the effects of oxidized low density lipoproteins (Ox-LDL) on aortic smooth muscle cell (SMC) proliferation… 
1991
1991
Metabolism of D-[3H]threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol, an inhibitor of glucosylceramide synthesis, and the synergistic action of an inhibitor of microsomal monooxygenase.
D-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (D-PDMP) is an effective inhibitor of the glucosyltransferase that makes… 
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