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germicidin

Known as: 6-(2-butyl)-3-ethyl-4-hydroxy-2-pyrone 
National Institutes of Health

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Broader (1)

Pyrones

Papers overview

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2019
2019
Production of New Antibacterial 4-Hydroxy-α-Pyrones by a Marine Fungus Aspergillus niger Cultivated in Solid Medium
Four 4-hydroxy-α-pyrones including three new ones named nipyrones A–C (1–3) together with one known analogue germicidin C (4… 
2019
2019
α-Pyrone derivatives with cyto-protective activity from two Takla Makan desert soil derived actinomycete Nocardiopsis strains recovered in seawater based medium
Abstract In this paper, we described the discovery of two Nocardiopsis strains HDN154-146 and HDN154-168 from Takla Makan desert… 
2017
2017
Germicidins H–J from Streptomyces sp. CB00361
α-Pyrones and natural products featuring an α-pyrone moiety are well known from bacteria,1 fungi,1 plants2 and animals,3 and they… 
2015
2015
A Streptomyces coelicolor host for the heterologous expression of Type III polyketide synthase genes
BackgroundRecent advances in genome sequencing, combined with bioinformatic analysis, has led to the identification of numerous… 
2012
2012
Biochemical and structural characterization of germicidin synthase: analysis of a type III polyketide synthase that employs acyl-ACP as a starter unit donor.
Germicidin synthase (Gcs) from Streptomyces coelicolor is a type III polyketide synthase (PKS) with broad substrate flexibility… 
2011
2011
Physiological role of germicidins in spore germination and hyphal elongation in Streptomyces coelicolor A3(2)
Four germicidin homologs were isolated from a liquid culture of Streptomyces coelicolor A3(2). These were identified as… 
Highly Cited
1993
Highly Cited
1993
Germicidin, an autoregulative germination inhibitor of Streptomyces viridochromogenes NRRL B-1551.
During germination spores of Streptomyces viridochromogenes NRRL B-1551 excrete a compound, germicidin, which has an inhibitory… 
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