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germicidin

Known as: 6-(2-butyl)-3-ethyl-4-hydroxy-2-pyrone 
 
National Institutes of Health

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Pyrones

Papers overview

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2019
2019
Production of New Antibacterial 4-Hydroxy-α-Pyrones by a Marine Fungus Aspergillus niger Cultivated in Solid Medium
Four 4-hydroxy-α-pyrones including three new ones named nipyrones A-C (1-3) together with one known analogue germicidin C (4… Expand
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2018
2018
α-Pyrone derivatives with cyto-protective activity from two Takla Makan desert soil derived actinomycete Nocardiopsis strains recovered in seawater based medium.
In this paper, we described the discovery of two Nocardiopsis strains HDN154-146 and HDN154-168 from Takla Makan desert soil… Expand
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2017
2017
Germicidins H–J from Streptomyces sp. CB00361
α-Pyrones and natural products featuring an α-pyrone moiety are well known from bacteria,1 fungi,1 plants2 and animals,3 and they… Expand
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2015
2015
A Streptomyces coelicolor host for the heterologous expression of Type III polyketide synthase genes
BackgroundRecent advances in genome sequencing, combined with bioinformatic analysis, has led to the identification of numerous… Expand
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2012
2012
Biochemical and structural characterization of germicidin synthase: analysis of a type III polyketide synthase that employs acyl-ACP as a starter unit donor.
Germicidin synthase (Gcs) from Streptomyces coelicolor is a type III polyketide synthase (PKS) with broad substrate flexibility… Expand
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2011
2011
Physiological role of germicidins in spore germination and hyphal elongation in Streptomyces coelicolor A3(2)
Four germicidin homologs were isolated from a liquid culture of Streptomyces coelicolor A3(2). These were identified as… Expand
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1993
1993
Germicidin, an autoregulative germination inhibitor of Streptomyces viridochromogenes NRRL B-1551.
During germination spores of Streptomyces viridochromogenes NRRL B-1551 excrete a compound, germicidin, which has an inhibitory… Expand
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