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fructosamine-3-kinase

National Institutes of Health

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FN3K gene

Papers overview

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2020
2020
Role of fructosamine-3-kinase in protecting against the onset of microvascular and macrovascular complications in patients with T2DM
Introduction Microangiopathic and macroangiopathic complications are the main cause of morbidity and mortality in the diabetic… 
Highly Cited
2019
Highly Cited
2019
The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase
2017
2017
Evidence That Differences in Fructosamine-3-Kinase Activity May Be Associated With the Glycation Gap in Human Diabetes
The phenomenon of a discrepancy between glycated hemoglobin levels and other indicators of average glycemia may be due to many… 
2010
2010
A polymorphism within the fructosamine-3-kinase gene is associated with HbA1c Levels and the onset of type 2 diabetes mellitus.
BACKGROUND Non-enzymatic glycation is a process, which leads to the formation of advanced glycation endproducts. These compounds… 
2006
2006
Magnesium-dependent Phosphatase-1 Is a Protein-Fructosamine-6-phosphatase Potentially Involved in Glycation Repair*
Fructosamine-3-kinase (FN3K) is a recently described protein-repair enzyme responsible for the removal of fructosamines, which… 
2005
2005
Some Clues as to the Regulation, Expression, Function, and Distribution of Fructosamine‐3‐Kinase and Fructosamine‐3‐Kinase‐Related Protein
Abstract: Fructosamine‐3‐kinase (FN3K) and the more recently discovered fructosamine‐3‐kinase‐related protein (FN3KRP) appear to… 
Highly Cited
2004
Highly Cited
2004
Identification of Fructosamine Residues Deglycated by Fructosamine-3-kinase in Human Hemoglobin*
Fructosamine-3-kinase (FN3K) phosphorylates fructosamine residues, leading to their destabilization and their shedding from… 
2004
2004
The expression of the genes for fructosamine-3-kinase and fructosamine-3-kinase-related protein appears to be constitutive and unaffected by environmental signals.
2003
2003
A mammalian protein homologous to fructosamine-3-kinase is a ketosamine-3-kinase acting on psicosamines and ribulosamines but not on fructosamines.
Fructosamine-3-kinase (FN3K) is an enzyme that appears to be responsible for the removal of fructosamines from proteins. In this… 
Highly Cited
2001
Highly Cited
2001
Human fructosamine-3-kinase: purification, sequencing, substrate specificity, and evidence of activity in vivo.
Nonenzymatic glycation appears to be an important factor in the pathogenesis of diabetic complications. Key early intermediates… 
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