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fluoroneplanocin A

Known as: 3-(adenin-9-yl)-2-fluoro-4,5-dihydroxy-1-hydroxymethyl-1-cyclopentene 
National Institutes of Health

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2 relations

Broader (1)

Adenosine
analogs & derivatives

Papers overview

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2011
2011
X-ray crystal structure and binding mode analysis of human S-adenosylhomocysteine hydrolase complexed with novel mechanism-based inhibitors, haloneplanocin A analogues.
The X-ray crystal structure of human S-adenosylhomocysteine (AdoHcy) hydrolase was first determined as a tetrameric form bound… 
2008
2008
Synthesis of pyrimidine analog of fluoroneplanocin A as potential anti-HCV agent.
N-hydroxycytosine nucleoside 3 was synthesized as potential anti-HCV agent, starting from D-ribose using an iodine-fluorine… 
2007
2007
Asymmetric Synthesis of Apio Fluoroneplanocin a Analogs as Potential AdoHcy Hydrolase Inhibitor
Apio fluoroneplanocin A (apio F-NPA, 3) and its uracil analogue 4 have been designed and asymmetrically synthesized starting from… 
Highly Cited
2003
Highly Cited
2003
Design, synthesis, and biological evaluation of fluoroneplanocin A as the novel mechanism-based inhibitor of S-adenosylhomocysteine hydrolase.
Fluoroneplanocin A (12) was designed as a novel mechanism-based inhibitor of S-adenosylhomocysteine hydrolase (SAH) and… 
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