flap endonuclease activity

Catalysis of the cleavage of a flap structure in DNA, but not other DNA structures; processes the ends of Okazaki fragments in lagging strand DNA… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2017
012319962017

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2014
2014
The carboxy-terminal binding protein (CtBP)-interacting protein (CtIP) is known to function in 5' strand resection during… (More)
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2014
2014
Flap endonucleases remove flap structures generated during DNA replication. Gene 6 protein of bacteriophage T7 is a 5'-3… (More)
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Highly Cited
2009
Highly Cited
2009
Structure-specific endonucleases resolve DNA secondary structures generated during DNA repair and recombination. The yeast 5… (More)
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2007
2007
Drosophila melanogaster XPG-like endonuclease (DmGEN) is a new category of nuclease belonging to the RAD2/XPG family. The DmGEN… (More)
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2002
2002
Flap endonuclease-1 (FEN-1) is a critical enzyme for DNA replication and repair. Intensive studies have been carried out on its… (More)
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2001
2001
In eukaryotes, the nuclease activity of Rad27p (Fen1p) is thought to play a critical role in lagging-strand DNA replication by… (More)
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Highly Cited
1999
Highly Cited
1999
The RAD2 family of nucleases includes human XPG (Class I), FEN1 (Class II), and HEX1/hEXO1 (Class III) products gene. These… (More)
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1999
1999
During V(D)J recombination, processing of branched coding end intermediates is essential for generating junctional diversity… (More)
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1997
1997
Human flap endonuclease-1 (hFEN-1) is highly homologous to human XPG, Saccharomyces cerevisiae RAD2 and S.cerevisiae RTH1 and… (More)
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1997
1997
Bacteriophage T4 RNase H is a 5'- to 3'-nuclease that has exonuclease activity on RNA.DNA and DNA.DNA duplexes and can remove the… (More)
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