FAQ

fatty acid elongase activity

Catalysis of the reaction: fatty acid (C-16 or longer) + 2-C = fatty acid (C-16 or longer + 2-C). [GOC:tb]

Topic mentions per year

Topic mentions per year

1999-2014
01219992014

Papers overview

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2014
2014
Endoplasmic reticulum microenvironment and conserved histidines govern ELOVL4 fatty acid elongase activity
Autosomal dominant Stargardt-like macular dystrophy (STGD3) in humans results from mutations in elongation of very long chain FAs… (More)
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2010
2010
Western diet changes cardiac acyl-CoA composition in obese rats: a potential role for hepatic lipogenesis.
The "lipotoxic footprint" of cardiac maladaptation in diet-induced obesity is poorly defined. We investigated how manipulation of… (More)
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2009
2009
High-throughput assay for long chain fatty acyl-CoA elongase using homogeneous scintillation proximity format.
Elongase of very-long-chain fatty acid (Elovl) 6 is a rate-limiting enzyme that is responsible for the elongation of long-chain… (More)
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2004
2004
Effect of exercise training on the fatty acid composition of lipid classes in rat liver, skeletal muscle, and adipose tissue
The aim of the present study was to examine the effects of 8 weeks of exercise training on the fatty acid composition of… (More)
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2004
2004
Gaining insight into the role of serine 282 in B. napus FAE1 condensing enzyme.
To gain some insight whether there is an absolute requirement for the serine 282 to yield a functional fatty acid elongase 1… (More)
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2002
2002
A Saccharomyces cerevisiae gene required for heterologous fatty acid elongase activity encodes a microsomal beta-keto-reductase.
A number of Saccharomyces cerevisiae membrane-bound oxidoreductases were examined for potential roles in microsomal fatty acid… (More)
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2001
2001
Active-site residues of a plant membrane-bound fatty acid elongase beta-ketoacyl-CoA synthase, FAE1 KCS.
The fatty acid elongase-1 beta-ketoacyl-CoA synthase, FAE1 KCS, a seed-specific elongase condensing enzyme from Arabidopsis, is… (More)
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1999
1999
Low C18 to C20 fatty acid elongase activity and limited conversion of stearidonic acid, 18:4(n-3), to eicosapentaenoic acid, 20:5(n-3), in a cell line from the turbot, Scophthalmus maximus.
The TF cell line, derived from a top predatory, carnivorous marine teleost, the turbot (Scophthalmus maximus), is known to have a… (More)
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