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fasitibant

 
National Institutes of Health

Papers overview

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2018
2018
Involvement of Bradykinin B2 Receptor in Pathological Vascularization in Oxygen-Induced Retinopathy in Mice and Rabbit Cornea
The identification of components of the kallikrein–kinin system in the vitreous from patients with microvascular retinal diseases… Expand
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2016
2016
Discovery of new selective antagonists of G-protein coupled receptors of therapeutic interest
GPCR are integral membrane receptor proteins that are characterized by heptahelical transmembrane domains connected by… Expand
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2015
2015
New insights into the stereochemical requirements of the bradykinin B2 receptor antagonists binding
Bradykinin (BK) is a member of the kinin family, released in response to inflammation, trauma, burns, shock, allergy and some… Expand
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2015
2015
of Computer-Aided Molecular Design NEW INSIGHTS INTO THE STEREOCHEMICAL REQUIREMENTS OF THE BRADYKININ B 2 RECEPTOR ANTAGONISTS
Abstract: Bradykinin (BK) is a member of the kinin family, released in response to inflammation, trauma, burns, shock, allergy… Expand
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2014
2014
Serum biomarkers detection clusters improve the detection of symptomatic treatment effect in knee osteoarthitis patients: the results of a phase ib/iia study with the b2 receptor antagonist…
 
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2013
2013
Blockade of nociceptive sensory afferent activity of the rat knee joint by the bradykinin B2 receptor antagonist fasitibant.
OBJECTIVE The aim of this study was to determine in intact and inflamed knee joints of the rat, the effect of the bradykinin (BK… Expand
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2012
2012
Fasitibant prevents the bradykinin and interleukin 1β synergism on prostaglandin E2 release and cyclooxygenase 2 expression in human fibroblast-like synoviocytes
This study investigates the effect of the selective and potent B2 receptor antagonist fasitibant (MEN16132) on the… Expand
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