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farnesyl thiopyrophosphate

Known as: FsPP cpd, farnesyl thiodiphosphate 
National Institutes of Health

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Broader (1)

Polyisoprenyl Phosphates

Papers overview

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2011
2011
Fluorescent substrate analog for monitoring chain elongation by undecaprenyl pyrophosphate synthase in real time.
Farnesyl pyrophosphate (FPP) is a common substrate for a variety of prenyltransferases for synthesizing isoprenoid compounds. In… Expand
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2011
2011
Head-to-head terpene synthases: Mechanism of action and inhibition
ion), PSPP, with the highly conserved Asp residues in the first DXXXD domain being essential for catalysis, Figure 2.3. To… Expand
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Highly Cited
2009
Highly Cited
2009
Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results.
The gold color of Staphylococcus aureus is derived from the carotenoid staphyloxanthin, a virulence factor for the organism. Here… Expand
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2008
2008
Biochemical and structural basis for feedback inhibition of mevalonate kinase and isoprenoid metabolism.
Mevalonate kinase (MK), which catalyzes a key reaction in polyisoprenoid and sterol metabolism in many organisms, is subject to… Expand
2004
2004
Staphylococcus aureus mevalonate kinase: isolation and characterization of an enzyme of the isoprenoid biosynthetic pathway.
It has been proposed that isoprenoid biosynthesis in several gram-positive cocci depends on the mevalonate pathway for conversion… Expand
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