evacetrapib
National Institutes of Health
Papers overview
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Genome-wide polygenic scores (GPSs) integrate information from many common DNA variants into a single measure of inherited…
Former baseball manager Tony La Russa once said, “Even when you have three strikes, you’re still not out. There is always…
Cholesteryl ester transfer protein (CETP) inhibitors are a drug class targeting the enzyme CETP (1). The first CETP inhibitor…
BACKGROUND
Evacetrapib, a new cholesteryl ester transfer protein inhibitor, is being investigated as a potential therapeutic…
Purpose of review To re-evaluate the functions of plasma cholesteryl ester transfer protein (CETP) in atherosclerosis based upon…
Evacetrapib is an investigational cholesteryl ester transfer protein inhibitor (CETPi) for reduction of risk of major adverse…
Purpose: To evaluate whether evacetrapib prolongs QT intervals in healthy participants. Methods: This was a single-center…
The plasma levels of high-density lipoprotein (HDL) cholesterol are inversely related to cardiovascular risk. Traditional HDL…
Background: As low HDL cholesterol levels are a risk factor for cardiovascular disease, raising HDL cholesterol substantially by…