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ethynerone
Known as:
17-alpha-chloroethynyl-19-nor-4,9-androstadien-17-beta-ol-3-one
, 19-nor-17-alpha-pregna-4,9-dien-20-yn-3-one, 21-chloro-17-hydroxy-
, 21-chloro-17-hydroxy-19-nor-17 alpha-pregna-4,9-dien- 20-yn-3-one
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1988
1988
The morphologic effects of synthetic reproductive steroids on the mammary gland of rhesus monkeys. Mestranol, ethynerone, mestranol-ethynerone, chloroethynyl norgestrel-mestranol, and anagestone…
F. Tavassoli
,
H. W. Casey
,
H. Norris
American Journal of Pathology
1988
Corpus ID: 23327228
A total of 213 treated and 16 control monkeys comprising 12 experimental groups was evaluated for determination of the long-term…
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1984
1984
Changes in estrogen metabolism after chronic oral contraceptive administration in the rhesus monkey.
W. Slikker
,
G. Lipe
,
T. J. Sziszak
,
J. Bailey
Drug Metabolism And Disposition
1984
Corpus ID: 22643480
The metabolism and elimination of estradiol (E2) and ethynylestradiol (EE2) were examined in adult female rhesus monkeys treated…
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1983
1983
Cytochrome P-450-dependent oxidation of the 17 alpha-ethynyl group of synthetic steroids. D-homoannulation or enzyme inactivation.
S. Schmid
,
W. Au
,
D. Hill
,
F. Kadlubar
,
W. Slikker
Drug Metabolism And Disposition
1983
Corpus ID: 21202977
Metabolism of the 17 alpha-ethynyl group of the synthetic estrogen, 17 alpha-ethynylestradiol, by hepatic microsomes from female…
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1980
1980
Malignant mammary tumors in beagle dogs dosed with investigational oral contraceptive steroids.
R. Kwapien
,
R. Giles
,
R. Geil
,
H. W. Casey
Journal of the National Cancer Institute
1980
Corpus ID: 11735154
Of 172 beagle dogs administered investigational oral contraceptive steroids for 2.4-5.2 years, 9 developed malignant mammary…
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1979
1979
The effects of a mixture of mestranol and ethynerone on the female monkey.
F. Coulston
,
A. Stein
,
D. Serrone
,
H. Jacobson
,
A. Phelps
,
H. Peck
Experimental and molecular pathology (Print)
1979
Corpus ID: 41283126
1978
1978
Mammary nodules in beagle dogs administered investigational oral contraceptive steroids.
R. Giles
,
R. Kwapien
,
R. Geil
,
H. W. Casey
Journal of the National Cancer Institute
1978
Corpus ID: 31205359
Of 172 beagle dogs administered oral contraceptive steroids for 5-7 years, 114 developed 1,156 nodules in the mammary gland…
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Review
1977
Review
1977
FDA studies of estrogen, progestogens, and estrogen/progestogen combinations in the dog and monkey.
R. Geil
,
J. Lamar
Journal of Toxicology and Environmental Health…
1977
Corpus ID: 36975196
A study begun by a drug company and taken over by the FDA (Food and Drug Administration) in 1970 attempted to assess the role…
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1977
1977
FDA studies of estrogen, progestogens, and estrogen/progestogen combinations in the dog and monkey.
Geil Rg
,
Lamar Jk
1977
Corpus ID: 227319195
In a study that has been in progress for 8 yr, ethynerone (MK 665) plus mestranol, chloroethynyi norgestrel (Wy‐4355) plus…
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1977
1977
Basaloid adenomas of the mammary gland in beagle dogs administered investigational contraceptive steroids.
R. Kwapien
,
R. Giles
,
R. Geil
,
H. W. Casey
Journal of the National Cancer Institute
1977
Corpus ID: 33642821
Clinical and morphologic characteristics of 82 basaloid adenomas (BAs) that developed in the mammary glands of 29 of 171 female…
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