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erythropoietin-mediated signaling pathway

Known as: EPO-R signaling pathway, erythropoietin receptor signaling pathway 
A series of molecular signals initiated by the binding of erythropoietin (EPO) to the erythropoietin receptor (EPO-R) on the surface of a cell, and… Expand
National Institutes of Health

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erythropoietin receptor activity

Papers overview

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2016
2016
The tumor promoting roles of erythropoietin/erythropoietin receptor signaling pathway in gastric cancer
Erythropoietin (EPO), binding with its receptor (EPOR), plays an important role in erythropoiesis. EPOR is reported to be… Expand
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2012
2012
The Erythropoietin/Erythropoietin Receptor Signaling Pathway Promotes Growth and Invasion Abilities in Human Renal Carcinoma Cells
Co-expression of erythropoietin (Epo) and erythropoietin receptor (EpoR) has been found in various non-hematopoietic cancers… Expand
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Highly Cited
2010
Highly Cited
2010
Erythropoietin Receptor Signaling Through STAT3 Is Required For Glioma Stem Cell Maintenance.
Recombinant erythropoietin (EPO) is a growth factor used in the treatment of chemotherapy-induced anemia, but recent studies… Expand
Highly Cited
2010
Highly Cited
2010
Role of Erythropoietin Receptor Signaling in Parvovirus B19 Replication in Human Erythroid Progenitor Cells
ABSTRACT Parvovirus B19 (B19V) infection is highly restricted to human erythroid progenitor cells. Although previous studies have… Expand
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2010
2010
Erythropoietin receptor signaling mitigates renal dysfunction-associated heart failure by mechanisms unrelated to relief of anemia.
OBJECTIVES We examined the effect of asialoerythropoietin (asialoEPO), a nonerythrogenic derivative of erythropoietin (EPO), on… Expand
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2008
2008
HLA-G turns off erythropoietin receptor signaling through JAK2 and JAK2 V617F dephosphorylation: clinical relevance in polycythemia vera
HLA-G5 is secreted by erythroblasts in all hematopoietic organs, suggesting a role for this protein in erythropoiesis. To examine… Expand
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2006
2006
Role of erythropoietin receptor signaling in Friend virus-induced erythroblastosis and polycythemia.
Friend virus is an acutely oncogenic retrovirus that causes erythroblastosis and polycythemia in mice. Previous studies suggested… Expand
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Highly Cited
2000
Highly Cited
2000
Protein Kinase C α Controls Erythropoietin Receptor Signaling*
Protein kinase C (PKC) is implied in the activation of multiple targets of erythropoietin (Epo) signaling, but its exact role in… Expand
Highly Cited
1999
Highly Cited
1999
Ineffective erythropoiesis in myelodysplastic syndromes: correlation with Fas expression but not with lack of erythropoietin receptor signal transduction
Ineffective erythropoiesis in myelodysplasia is characterized by a defect in erythroid progenitor growth and by abnormal… Expand
Highly Cited
1995
Highly Cited
1995
Involvement of SH2-containing Phosphotyrosine Phosphatase Syp in Erythropoietin Receptor Signal Transduction Pathways (*)
Erythropoietin (Epo) regulates the proliferation and differentiation of erythroid precursors. The phosphorylation of proteins at… Expand
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