erythronolide synthase activity

Known as: erythronolide condensing enzyme activity, malonyl-CoA:propionyl-CoA malonyltransferase (cyclizing) 
Catalysis of the reaction: 6 malonyl-CoA + propionyl-CoA = 7 CoA + 6-deoxyerythronolide B. [EC:2.3.1.94, MetaCyc:ERYTHRONOLIDE-SYNTHASE-RXN]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2014
0119752014

Papers overview

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2014
2014
The P450eryF enzyme (CYP107A1) hydroxylates 6-deoxyerythronolide B to erythronolide B during erythromycin synthesis by… (More)
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2001
2001
Using a previously developed expression system based on the erythromycin-producing strain of Saccharopolyspora erythraea, O… (More)
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1992
1992
Previous studies of erythromycin biosynthesis have indicated that a cytochrome P-450 monooxygenase system is responsible for… (More)
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1988
1988
The hydroxylation of 6-deoxyerythronolide B (6D) to erythronolide B, a step in the biosynthesis of the 14-membered macrolide… (More)
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