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erythronolide synthase activity

Known as: erythronolide condensing enzyme activity, malonyl-CoA:propionyl-CoA malonyltransferase (cyclizing) 
Catalysis of the reaction: 6 malonyl-CoA + propionyl-CoA = 7 CoA + 6-deoxyerythronolide B. [EC:2.3.1.94, MetaCyc:ERYTHRONOLIDE-SYNTHASE-RXN]
National Institutes of Health