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erythronolide synthase activity

Known as: erythronolide condensing enzyme activity, malonyl-CoA:propionyl-CoA malonyltransferase (cyclizing) 
Catalysis of the reaction: 6 malonyl-CoA + propionyl-CoA = 7 CoA + 6-deoxyerythronolide B. [EC:2.3.1.94, MetaCyc:ERYTHRONOLIDE-SYNTHASE-RXN]
National Institutes of Health

Papers overview

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1996
1996
5-0-desosaminyl 6-0-methyl erythronolide A, their methods of preparation and their use for preparing a drug-
1996
1996
Derivatives of 5-0-desosaminyl-6-0-methyl erythronolide A, their process of preparation and use for producing medicaments
1992
1992
Sythesis of Erythronolide A via Direct Macrolactonization of a Conformationally Controlled Seco-acid with the Yamaguchi Reagent in the Presence of Dimethylaminopyridine
1973
1973
Limiting Reactions in Activation of Acyl Units in Biosynthesis of Macrolide Antibiotics
Formation of propionyl phosphate in Streptomyces erythreus synthesizing a polypropionate erythronolide ring of erythromycin was… 
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