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error-free translesion synthesis

The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Genetic evidence for reconfiguration of DNA polymerase θ active site for error-free translesion synthesis in human cells
The action mechanisms revealed by the biochemical and structural analyses of replicative and translesion synthesis (TLS) DNA… 
2017
2017
A Novel Histone Crosstalk Pathway Important for Regulation of UV-Induced DNA Damage Repair in Saccharomyces cerevisiae
Histone post-translational modifications play vital roles in a variety of nuclear processes, including DNA repair. It has been… 
2016
2016
Histone H2B mono-ubiquitylation maintains genomic integrity at stalled replication forks
Histone modifications play an important role in regulating access to DNA for transcription, DNA repair and DNA replication. A… 
Review
2015
Review
2015
Roles of mutagenic translesion synthesis in mammalian genome stability, health and disease.
2011
2011
Oxidative DNA Damage Bypass in Arabidopsis thaliana Requires DNA Polymerase λ and Proliferating Cell Nuclear Antigen 2[W]
The common oxidative DNA lesion 8-oxoguanine is highly mutagenic. Here, we show that, in Arabidopsis, DNA polymerase λ plays a… 
Highly Cited
2010
Highly Cited
2010
The molecular chaperone Hsp90 regulates accumulation of DNA polymerase eta at replication stalling sites in UV-irradiated cells.
Highly Cited
2004
Highly Cited
2004
The Role of DNA Polymerase η in Translesion Synthesis Past Platinum–DNA Adducts in Human Fibroblasts
Cisplatin, a widely used chemotherapeutic agent, has been implicated in the induction of secondary tumors in cancer patients… 
Highly Cited
2002
Highly Cited
2002
Requirement of RAD5 and MMS2 for Postreplication Repair of UV-Damaged DNA in Saccharomyces cerevisiae
ABSTRACT UV lesions in the template strand block the DNA replication machinery. Genetic studies of the yeast Saccharomyces… 
Highly Cited
2000
Highly Cited
2000
Error-prone lesion bypass by human DNA polymerase eta.
DNA lesion bypass is an important cellular response to genomic damage during replication. Human DNA polymerase eta (Pol(eta… 
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