error-free translesion synthesis

The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2016
0119982016

Papers overview

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2017
2017
Histone post-translational modifications play vital roles in a variety of nuclear processes, including DNA repair. It has been… (More)
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2016
2016
Histone modifications play an important role in regulating access to DNA for transcription, DNA repair and DNA replication. A… (More)
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2014
2014
Reactive oxygen species generate many lesions in DNA, including R and S diastereomers of 8,5'-cyclo-2'-deoxyadenosine (cdA) and 8… (More)
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2011
2011
The oxidized base 7,8-oxoguanine (8-oxo-G) is the most common DNA lesion generated by reactive oxygen species. This lesion is… (More)
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2010
2010
DNA polymerase eta (Pol eta) is a member of the mammalian Y family polymerases and performs error-free translesion synthesis… (More)
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2004
2004
Cisplatin, a widely used chemotherapeutic agent, has been implicated in the induction of secondary tumors in cancer patients… (More)
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Highly Cited
2002
Highly Cited
2002
UV lesions in the template strand block the DNA replication machinery. Genetic studies of the yeast Saccharomyces cerevisiae have… (More)
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2000
2000
DNA lesion bypass is an important cellular response to genomic damage during replication. Human DNA polymerase eta (Pol(eta… (More)
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1998
1998
The Escherichia coli NarI restriction enzyme recognition site 5'G1G2C3G4C5C63' is a mutational hotspot for -2 deletions in E… (More)
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