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error-free translesion synthesis
The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or…
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Genetic evidence for reconfiguration of DNA polymerase θ active site for error-free translesion synthesis in human cells
J. Yoon
,
Robert E. Johnson
,
L. Prakash
,
S. Prakash
Journal of Biological Chemistry
2020
Corpus ID: 212707077
The action mechanisms revealed by the biochemical and structural analyses of replicative and translesion synthesis (TLS) DNA…
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2017
2017
A Novel Histone Crosstalk Pathway Important for Regulation of UV-Induced DNA Damage Repair in Saccharomyces cerevisiae
A. Boudoures
,
Jacob Pfeil
,
+5 authors
Jeffrey S. Thompson
Genetics
2017
Corpus ID: 32756642
Histone post-translational modifications play vital roles in a variety of nuclear processes, including DNA repair. It has been…
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2016
2016
Histone H2B mono-ubiquitylation maintains genomic integrity at stalled replication forks
Matthew R. Northam
,
K. Trujillo
Nucleic Acids Research
2016
Corpus ID: 11115587
Histone modifications play an important role in regulating access to DNA for transcription, DNA repair and DNA replication. A…
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Review
2015
Review
2015
Roles of mutagenic translesion synthesis in mammalian genome stability, health and disease.
J. Jansen
,
Anastasia Tsaalbi-Shtylik
,
N. de Wind
DNA Repair
2015
Corpus ID: 38413372
2011
2011
Oxidative DNA Damage Bypass in Arabidopsis thaliana Requires DNA Polymerase λ and Proliferating Cell Nuclear Antigen 2[W]
A. Amoroso
,
L. Concia
,
+5 authors
G. Maga
The Plant Cell
2011
Corpus ID: 2007566
The common oxidative DNA lesion 8-oxoguanine is highly mutagenic. Here, we show that, in Arabidopsis, DNA polymerase λ plays a…
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Highly Cited
2010
Highly Cited
2010
The molecular chaperone Hsp90 regulates accumulation of DNA polymerase eta at replication stalling sites in UV-irradiated cells.
T. Sekimoto
,
T. Oda
,
+4 authors
T. Yamashita
Molecules and Cells
2010
Corpus ID: 16370266
Highly Cited
2004
Highly Cited
2004
The Role of DNA Polymerase η in Translesion Synthesis Past Platinum–DNA Adducts in Human Fibroblasts
E. Bassett
,
N. M. King
,
+4 authors
M. Cordeiro‐Stone
Cancer Research
2004
Corpus ID: 19228328
Cisplatin, a widely used chemotherapeutic agent, has been implicated in the induction of secondary tumors in cancer patients…
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Highly Cited
2002
Highly Cited
2002
Requirement of RAD5 and MMS2 for Postreplication Repair of UV-Damaged DNA in Saccharomyces cerevisiae
C. Torres-Ramos
,
S. Prakash
,
L. Prakash
Molecular and Cellular Biology
2002
Corpus ID: 25822441
ABSTRACT UV lesions in the template strand block the DNA replication machinery. Genetic studies of the yeast Saccharomyces…
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Highly Cited
2000
Highly Cited
2000
Error-prone lesion bypass by human DNA polymerase eta.
Y. Zhang
,
F. Yuan
,
+4 authors
Z. Wang
Nucleic Acids Research
2000
Corpus ID: 24853782
DNA lesion bypass is an important cellular response to genomic damage during replication. Human DNA polymerase eta (Pol(eta…
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