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error-free translesion synthesis

The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or… Expand
National Institutes of Health

Papers overview

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2020
2020
The action mechanisms revealed by the biochemical and structural analyses of replicative and translesion synthesis (TLS) DNA… Expand
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2017
2017
Histone post-translational modifications play vital roles in a variety of nuclear processes, including DNA repair. It has been… Expand
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2016
2016
Histone modifications play an important role in regulating access to DNA for transcription, DNA repair and DNA replication. A… Expand
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Review
2015
Review
2015
Most spontaneous and DNA damage-induced nucleotide substitutions in eukaryotes depend on translesion synthesis polymerases Rev1… Expand
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2011
2011
The common oxidative DNA lesion 8-oxoguanine is highly mutagenic. Here, we show that, in Arabidopsis, DNA polymerase λ plays a… Expand
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2010
2010
DNA polymerase eta (Pol eta) is a member of the mammalian Y family polymerases and performs error-free translesion synthesis… Expand
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Highly Cited
2004
Highly Cited
2004
Cisplatin, a widely used chemotherapeutic agent, has been implicated in the induction of secondary tumors in cancer patients… Expand
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Highly Cited
2002
Highly Cited
2002
UV lesions in the template strand block the DNA replication machinery. Genetic studies of the yeast Saccharomyces cerevisiae have… Expand
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Highly Cited
2000
Highly Cited
2000
DNA lesion bypass is an important cellular response to genomic damage during replication. Human DNA polymerase eta (Pol(eta… Expand
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