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erastin

National Institutes of Health

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Piperazines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Letter to the editor: iron, apoptosis, and ferroptosis
A unique chemistry led to the evolutionary selection of iron for a wide range of fundamental cell functions, and the availability… 
2019
2019
Novel mouse model for evaluating in vivo efficacy of xCT inhibitor.
2019
2019
Ferroptosis is programmed by the coordinated regulation of glutathione and iron metabolism by BACH1
Ferroptosis is an iron-dependent programmed cell death resulting from alterations of metabolic processes. However, its regulation… 
2018
2018
Comment on “Targeting AMPK, mTOR and β-Catenin by Combined Metformin and Aspirin Therapy in HCC: An Appraisal in Egyptian HCC Patients”
2018
2018
miR-9 regulates ferroptosis by targeting glutamic-oxaloacetic transaminase GOT 1 in melanoma † Running Title : miR-9 regulates ferroptosis in melanoma
Kexin Zhang, Longfei Wu, Peng Zhang, Meiying Luo, Jing Du, Tongtong Gao, Douglas O’Connell, Gaoyang Wang, Hong Wang and Yongfei… 
2018
2018
Abstract 2321: Molecular crosstalk between ferroptosis and apoptosis: Emerging role of ER stress-induced p53-independent PUMA expression
Ferroptosis is a type of programmed cell death that depends on iron and is characterized by the accumulation of lipid peroxides… 
2018
2018
Abstract 2322: Ferroptosis induced by erastin in RAS mutant ovarian cancer cells
Although apoptosis has been thought as the principal mechanism of programed cell death in chemotherapy, other forms of non… 
2017
2017
PREDICTIVE MODELS FOR SYSTEM X C- ANTIPORTER INHIBITION BASED ON STRUCTURALLY DIVERSE MOLECULES
: The morbidity and mortality throughout the world is increasing day by day due to cancer. Several molecular targets have been… 
2011
2011
Functional Model of Metabolite Gating by Human Voltage-Dependent Anion Channel 2
Voltage-dependent anion channels (VDACs) are critical regulators of outer mitochondrial membrane permeability in eukaryotic cells… 
Review
2007
Review
2007
Chemical genetic approaches to probing cell death.
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