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equol, (-)-

Known as: S-equol, (-)-Equol, (3S)-3,4-dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol 
An orally bioavailable, non-steroidal estrogen naturally produced by the metabolism of the isoflavonoid daidzein by human intestinal microflora, with… 
National Institutes of Health

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Broader (1)

Equol
NCIt Antineoplastic Agent Terminologyequol, (+)

Papers overview

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2018
2018
Incomplete metabolism of phytoestrogens by gut microbiota from children under the age of three
Abstract Phytoestrogens are plant-derived polyphenols with structural and functional similarities to mammalian oestrogens. The… 
2015
2015
The Effect of Eqoul, a Metabolite of Isoflavone, on Endothelial Cell-independent Vasodilatation of Human Uterine Artery In Vitro
Background The purpose of this study is to investigate 1) whether equol has the direct modulation on vascular tone of endothelium… 
2013
2013
Development of a food compositional database for the estimation of dietary intake of phyto-oestrogens in a group of postmenopausal women previously treated for breast cancer and validation with…
The scientific literature contains evidence suggesting that women who have been treated for breast cancer may, as a result of… 
2012
2012
Soya isoflavone consumption in relation to carotid intima–media thickness in Chinese equol excretors aged 40–65 years
Previous studies have suggested that the daidzein metabolite equol rather than daidzein itself contributes to the beneficial… 
2010
2010
The Journal of Nutrition Supplement : Equol , Soy , and Menopause Cautions and Research Needs Identified at the Equol , Soy , and Menopause Research Leadership Conference 1 – 3
This summary addresses the progress and limitations of existing research on the physiologic properties of the isoflavone daidzein… 
2010
2010
Endocrine and safety assessment pre‐ and post‐ingestion of Natural S‐equol for 12 weeks in healthy Japanese adult males
S‐equol is an intestinal bacterial metabolite of daidzein. S‐equol is produced by 50% of Japanese but only 30% of North Americans… 
2007
2007
Pharmacokinetics of an Equol Supplement in Humans
Equol, a metabolite of daidzein, is considered to be the most effective estrogen modifier in the human body. The production of… 
2006
2006
Urinary isoflavonoids as a dietary compliance measure among premenopausal women.
Clinical trials investigating the effects of soy food intake require high compliance with a dietary protocol. Measuring soy… 
2005
2005
Protective Effect of the Isoflavonoid Equol Against Hairless Mouse Skin Carcinogenesis Induced by UV Radiation Alone or with a Chemical Cocarcinogen ¶
Isoflavones derived from many edible plants, such as genistein from the soybean, have well‐documented antioxidant and estrogenic… 
2001
2001
Human Nutrition and Metabolism Wheat Bran and Soy Protein Feeding Do Not Alter Urinary Excretion of the Isoflavan Equol in Premenopausal Women 1
The capacity to convert the soy isoflavone daidzein to equol in vivo is presumably determined by an individual’s intestinal… 
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