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epelsiban

Known as: (3R,6R)-3-(2,3-Dihydro-1H-inden-2-yl)-1-((1R)-1-(2,6-dimethylpyridin-3-yl)-2-(morpholin- 4-yl)-2-oxoethyl)-6-((1S)-1-methylpropyl)piperazine-2,5-dione, (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)-1-((1R)-1-(2,6- dimethylpyridin-3-yl)-2-(morpholin- 4-yl)-2-oxoethyl)-6- ((1S)-1-methylpropyl)piperazine-2,5-dione, 2,5-piperazinedione, 3-(2,3-dihydro-1h-inden-2-yl)-1-((1R)-1-(2,6-dimethyl-3-pyridinyl)-2-(4-morpholinyl)-2-oxoethyl)-6-((1S)-1-methylpropyl)-, (3R,6R)- 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

DiketopiperazinesMorpholines
Epelsiban Besylate

Narrower (1)

GSK557296

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Functionally selective inhibition of the oxytocin receptor by retosiban in human myometrial smooth muscle.
CONTEXT Novel small molecule inhibitors of the oxytocin receptor (OTR) may have distinct pharmacology and mode of action when… 
2018
2018
Single‐ and Multiple‐Day Dosing Studies to Investigate High‐Dose Pharmacokinetics of Epelsiban and Its Metabolite, GSK2395448, in Healthy Female Volunteers
Open‐label single‐ and double‐blind repeat‐dose studies in healthy female volunteers were conducted to investigate the… 
2015
2015
A single‐ and multiple‐dose study to investigate the pharmacokinetics of epelsiban and its metabolite, GSK2395448, in healthy female volunteers
An open‐label single‐ and repeat‐dose study was conducted to investigate the pharmacokinetics, safety, and tolerability of… 
Highly Cited
2006
Highly Cited
2006
Pyridyl-2,5-diketopiperazines as potent, selective, and orally bioavailable oxytocin antagonists: synthesis, pharmacokinetics, and in vivo potency.
A six-stage stereoselective synthesis of indanyl-7-(3'-pyridyl)-(3R,6R,7R)-2,5-diketopiperazines oxytocin antagonists from indene… 
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