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entecavir

Known as: ETV, entecavir [Chemical/Ingredient], 6H-Purin-6-One, 2-Amino-1,9-Dihydro-9-((1S,3R,4S)-4-Hydroxy-3-(Hydroxymethyl)-2-Methylenecyclopentyl)- Monohydrate 
A synthetic analog of 2-deoxyguanosine with antiviral activity against hepatitis B virus (HBV). Entecavir is activated in vivo to a 5-triphosphate… Expand
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Hepatitis B virus (HBV) infection remains a global public health problem with changing epidemiology due to several factors… Expand
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Highly Cited
2013
Highly Cited
2013
Chronic hepatitis B virus (HBV) infection leads to cirrhosis and hepatocellular carcinoma (HCC). Antiviral agents are thought to… Expand
Review
2012
Review
2012
Large volume of new data on the natural history and treatment of chronic hepatitis B virus (HBV) infection have become available… Expand
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Highly Cited
2010
Highly Cited
2010
One year of treatment with entecavir (0.5 mg daily) in nucleoside‐naive patients with hepatitis B e antigen (HBeAg)‐positive or… Expand
Highly Cited
2010
Highly Cited
2010
Sustained virologic suppression is a primary goal of therapy for chronic hepatitis B (CHB). In study entecavir (ETV)‐022, 48… Expand
Highly Cited
2009
Highly Cited
2009
Patients with chronic hepatitis B virus (HBV) infection who develop antiviral resistance lose benefits of therapy and may be… Expand
Highly Cited
2007
Highly Cited
2007
BACKGROUND & AIMS Entecavir demonstrated superior benefit to lamivudine at 48 weeks in nucleoside-naive patients with hepatitis B… Expand
Highly Cited
2006
Highly Cited
2006
BACKGROUND Entecavir is a potent and selective guanosine analogue with significant activity against hepatitis B virus (HBV… Expand
Highly Cited
2006
Highly Cited
2006
BACKGROUND Entecavir is a potent and selective antiviral agent that has demonstrated efficacy in phase 2 studies in patients with… Expand
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Review
2004
Review
2004
  • D. Lavanchy
  • Journal of viral hepatitis
  • 2004
  • Corpus ID: 163757
Summary.  Hepatitis B virus (HBV) infection is a serious global health problem, with 2 billion people infected worldwide, and 350… Expand