entecavir

Known as: ETV, entecavir [Chemical/Ingredient], 6H-Purin-6-One, 2-Amino-1,9-Dihydro-9-((1S,3R,4S)-4-Hydroxy-3-(Hydroxymethyl)-2-Methylenecyclopentyl)- Monohydrate 
A synthetic analog of 2-deoxyguanosine with antiviral activity against hepatitis B virus (HBV). Entecavir is activated in vivo to a 5-triphosphate… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
UNLABELLED Chronic hepatitis B virus (HBV) infection leads to cirrhosis and hepatocellular carcinoma (HCC). Antiviral agents are… (More)
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Highly Cited
2013
Highly Cited
2013
UNLABELLED Entecavir is a potent antiviral agent with high genetic barrier to resistance, hence it is currently recommended as… (More)
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Highly Cited
2010
Highly Cited
2010
UNLABELLED One year of treatment with entecavir (0.5 mg daily) in nucleoside-naive patients with hepatitis B e antigen (HBeAg… (More)
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Highly Cited
2010
Highly Cited
2010
UNLABELLED Sustained virologic suppression is a primary goal of therapy for chronic hepatitis B (CHB). In study entecavir (ETV… (More)
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Highly Cited
2009
Highly Cited
2009
UNLABELLED Patients with chronic hepatitis B virus (HBV) infection who develop antiviral resistance lose benefits of therapy and… (More)
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Highly Cited
2009
Highly Cited
2009
The 2009 update of the American Association for the Study of Liver Diseases (AASLD) Practice Guidelines for Management of Chronic… (More)
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Highly Cited
2009
Highly Cited
2009
Entecavir is a potent nucleoside inhibitor of the hepatitis B virus (HBV) polymerase with a high antiviral efficacy and a high… (More)
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Highly Cited
2007
Highly Cited
2007
Entecavir, a drug approved by the Food and Drug Administration for the treatment of chronic hepatitis B virus (HBV) infection, is… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND & AIMS Lamivudine treatment is associated with frequent development of resistant hepatitis B virus (HBV) and loss of… (More)
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Highly Cited
2004
Highly Cited
2004
Entecavir (ETV) exhibits potent antiviral activity in patients chronically infected with wild-type or lamivudine (3TC)-resistant… (More)
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