FAQ

enone reductase activity

Catalysis of the reaction: an enone + NADPH + H+ = a ketone + NADP+. [GOC:kad, PMID:17945329, PMID:19166903]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2016
01219952016

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2016
2016
Progesterone 5β-reductases/iridoid synthases (PRISE): gatekeeper role of highly conserved phenylalanines in substrate preference and trapping is supported by molecular dynamics simulations.
Vein Patterning 1 (VEP1)-encoded progesterone 5β-reductases/iridoid synthases (PRISE) belong to the short-chain dehydrogenase… (More)
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2013
2013
Total synthesis of (-)-18-epi-peloruside A: an alkyne linchpin strategy.
A convergent synthetic route toward cytotoxic agent peloruside A that hinges on the use of an alkyne linchpin to assemble the… (More)
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2013
2013
Formal total synthesis of spirangien A.
A formal total synthesis of the spiroketal containing cytotoxic myxobacteria metabolite spirangien A (1) is described. The… (More)
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2012
2012
Up-regulation of human prostaglandin reductase 1 improves the efficacy of hydroxymethylacylfulvene, an antitumor chemotherapeutic agent.
Prostaglandin reductase 1 (PTGR1) is a highly inducible enzyme with enone reductase activity. Previous studies demonstrated the… (More)
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2010
2010
(1R)-(+)-camphor and acetone derived alpha'-hydroxy enones in asymmetric Diels-Alder reaction: catalytic activation by Lewis and Brønsted acids, substrate scope, applications in syntheses, and…
The Diels-Alder reaction constitutes one of the most powerful and convergent C-C bond-forming transformations and continues to be… (More)
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2010
2010
One-pot synthesis of aminoenone via direct reaction of the chloroalkyl enone with NaN3: rapid access to polycyclic alkaloids.
A new one-pot procedure for the preparation of aminoenone from chloroalkyl enone and sodium azide was demonstrated. The structure… (More)
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2008
2008
Catalytic Michael reactions of ketoesters with a camphor-derived acrylate equivalent: stereoselective access to all-carbon quaternary centers.
A camphor-based alpha'-hydroxy enone reagent acts as a chiral acrylate equivalent in copper-catalyzed Michael reactions of beta… (More)
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1995
1995
Structure-related insect antifeedant and growth regulating activities of some limonoids
Insect antifeedant and growth-regulating activities of 22 limonoids (both natural and their derivatives) againstSpodoptera litura… (More)
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