endoderm development

The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the… (More)
National Institutes of Health

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Highly Cited
2004
Highly Cited
2004
BACKGROUND Studies in many model systems have shown that canonical signaling through the pathway downstream of ligands of the Wnt… (More)
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Review
2003
Review
2003
Recent studies in zebrafish have contributed to our understanding of early endoderm formation in vertebrates. Specifically, they… (More)
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Highly Cited
2002
Highly Cited
2002
In the mouse, the definitive endoderm is derived from the epiblast during gastrulation, and, at the early organogenesis stage… (More)
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Highly Cited
2001
Highly Cited
2001
Previous studies have indicated that gata5, a zinc-finger transcription factor gene, is required for the development of the… (More)
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Highly Cited
1999
Highly Cited
1999
The mechanisms regulating vertebrate heart and endoderm development have recently become the focus of intense study. Here we… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Several potentially important regulators of vertebrate endoderm development have been identified, including Activin… (More)
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Highly Cited
1999
Highly Cited
1999
The cellular and molecular mechanisms that regulate endoderm development in vertebrates have only recently begun to be explored… (More)
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Highly Cited
1998
Highly Cited
1998
Gene inactivation studies have shown that members of the GATA family of transcription factors are critical for endoderm… (More)
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Highly Cited
1998
Highly Cited
1998
Mutations in the SMAD4/DPC4 tumor suppressor gene, a key signal transducer in most TGFbeta-related pathways, are involved in 50… (More)
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Highly Cited
1996
Highly Cited
1996
In vertebrates, transcriptional regulators of the GATA family appear to have a conserved function in differentiation and organ… (More)
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