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endocardial cushion development

The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region… Expand
National Institutes of Health

Papers overview

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2011
2011
Cardiac valves originate from endocardial cushions (EC) formed by endothelial-to-mesenchymal transformation (EMT) during… Expand
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Highly Cited
2011
Highly Cited
2011
We report that the dominant human missense mutations G303E and G296S in GATA4, a cardiac-specific transcription factor gene… Expand
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2009
2009
The development of the valves and septa of the heart depends on the formation and remodeling of endocardial cushions. Here, we… Expand
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2007
2007
Development of the heart valves is a complex process that relies on the successful remodeling of endocardial cushions. This… Expand
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2006
2006
Atrioventricular septal defect occurs with a high prevalence in both human Down syndrome (trisomy 21) and the animal model for… Expand
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2004
2004
Development of the endocardial cushions in the heart involves cell migration and cell differentiation, which is known as… Expand
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Highly Cited
2003
Highly Cited
2003
Endocardial cushions are precursors of mature heart valves. They form within the looped heart tube as discrete swellings and… Expand
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Highly Cited
2003
Highly Cited
2003
Tbx20 is a member of the T-box transcription factor family expressed in the forming hearts of vertebrate and invertebrate embryos… Expand
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Highly Cited
2002
Highly Cited
2002
The formation of endocardial cushions in the atrioventricular (AV) canal of the rudimentary heart requires epithelial-to… Expand
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1981
1981
Retinoic acid (RA) (78mg/kg) administered to ICR mice on days 9.0,9.5 and 10.0 of pregnancy (plug day = day 1), resulted in… Expand
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