endocardial cushion development

The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2017
012319762017

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2013
2013
Cardiac valves are essential to direct forward blood flow through the cardiac chambers efficiently. Congenital valvular defects… (More)
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2011
2011
Cardiac valves originate from endocardial cushions (EC) formed by endothelial-to-mesenchymal transformation (EMT) during… (More)
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2011
2011
The atrioventricular canal (AVC) physically separates the atrial and ventricular chambers of the heart and plays a crucial role… (More)
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Highly Cited
2009
Highly Cited
2009
Notch signaling is vital for proper cardiovascular development and function in both humans and animal models. Indeed, mutations… (More)
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2008
2008
Twist1 is a bHLH transcription factor that regulates cell proliferation, migration, and differentiation in embryonic progenitor… (More)
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2008
2008
The endocardial cushions play a critical role in septation of the four-chambered mammalian heart and in the formation of the… (More)
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Highly Cited
2005
Highly Cited
2005
Defects in cardiac valve morphogenesis and septation of the heart chambers constitute some of the most common human congenital… (More)
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2003
2003
Endocardial cushions are precursors of mature heart valves. They form within the looped heart tube as discrete swellings and… (More)
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Highly Cited
2002
Highly Cited
2002
The formation of endocardial cushions in the atrioventricular (AV) canal of the rudimentary heart requires epithelial-to… (More)
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1996
1996
Atrioventricular septal defect occurs with a high prevalence in both human Down syndrome (trisomy 21) and the animal model for… (More)
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