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elisidepsin

Known as: L-Valine, N-((4S)-4-methyl-1-oxohexyl)-D-valyl-L-threonyl-L-valyl-D-valyl-D-prolyl-L-ornithyl-D-alloisoleucyl-D-allothreonyl-D-alloisoleucyl-D-valyl-L-phenylalanyl-(2Z)-2-amino-2-butenoyl-, (13-8)-lactone, 2,2,2-trifluoroacetate (1:1) 
A synthetic cyclic depsipeptide of the kahalalides family with potential antineoplastic activity. PM02734 is a derivative of a natural marine… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Depsipeptides

Narrower (2)

IrvalecPM02734

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Elisidepsin es un compuesto antitumoral de origen marino que causa muerte celular por necrosis relacionada con el contenido lipídico de las líneas celulares tumorales
Elisidepsin es un compuesto sintetico producido por PharmaMar S.A, derivado de un compuesto natural de origen marino. Tiene… 
2012
2012
ErbB 3 expression predicts sensitivity to elisidepsin treatment : In vitro synergism with cisplatin , paclitaxel and gemcitabine in lung , breast and colon cancer cell lines
Irvalec® (elisidepsin trifluoroacetate, PM02734) is a novel marine-derived cyclic peptide belonging to the Kahaladide family of… 
2012
2012
The mechanism of action of elisidepsin involves a direct hit on the plasma membrane
Background: Elisidepsin (PM02734, Irvalec ® ) is a synthetic compound whose structure is closely related to that of Kahalalide F… 
2012
2012
Study of the tumor sensitivity of the marine compound elisidepsin and her3 receptor in breast carcinomas
Elisidepsin es un nuevo depsipeptido sintetico resultante del programa de investigacion interna de PharmaMar para la obtencion de… 
2009
2009
Gateways to clinical trials.
[Methoxy-(11)C]PD-153035, 2-Methoxyestradiol; Adalimumab, Adecatumumab, Adefovir dipivoxil, ADH-1, ADX-10059, Aflibercept, AIR… 
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