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eleutherobin

 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Marine organisms produce a wide array of fascinating terpenoid structures distinguished by characteristic structural features… Expand
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2003
2003
A short and efficient RCM route is reported for the construction of the key nine-membered B ring of eleutherobin starting from… Expand
2003
2003
[reaction: see text] A synthesis of 28, the carbon framework of the eleutherobin aglycone, is reported in a 15-step sequence from… Expand
Highly Cited
2002
Highly Cited
2002
Laulimalide is a cytotoxic natural product that stabilizes microtubules. The compound enhances tubulin assembly, and laulimalide… Expand
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Highly Cited
2000
Highly Cited
2000
We describe a cell-based assay for antimitotic compounds that is suitable for drug discovery and for quantitative determination… Expand
Highly Cited
2000
Highly Cited
2000
Recently, three natural products have been identified, the epothilones, eleutherobin, and discodermolide, whose mechanism of… Expand
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Highly Cited
1999
Highly Cited
1999
Taxol (paclitaxel), a complex diterpene obtained from the Pacific yew, Taxus brevifolia, is arguably the most important new drug… Expand
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Highly Cited
1999
Highly Cited
1999
We examined interactions with purified tubulin of synthetic sarcodictyins A and B and eleutherobin (coral-derived antimitotic… Expand
Highly Cited
1998
Highly Cited
1998
Eleutherobin is a novel natural product isolated from a marine soft coral that is extremely potent for inducing tubulin… Expand
Highly Cited
1998
Highly Cited
1998
An "sp2 -sp3 Stille coupling" of the vinyl triflate 1 and the stannyl compound 2 is a key step toward the completion of the total… Expand