egg activation

The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or… (More)
National Institutes of Health

Papers overview

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2012
2012
Mammalian fertilization is accompanied by oscillations in egg cytoplasmic calcium (Ca(2+)) concentrations that are critical for… (More)
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Highly Cited
2010
Highly Cited
2010
Fertilization triggers a rise in intracellular Ca(2+) concentration ([Ca(2+)](i)) in the egg that initiates a series of events… (More)
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Review
2006
Review
2006
A dramatic increase in intracellular Ca(2+) concentration ([Ca(2+)](i)) occurs in eggs at fertilization common to all animal… (More)
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2006
2006
Activation of mature oocytes initiates development by releasing the prior arrest of female meiosis, degrading certain maternal… (More)
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2006
2006
Egg activation in mammals is caused by cytosolic Ca(2+) oscillations that are essential for development. However, despite… (More)
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2005
2005
Parthenogenetic agents that evoke cytosolic calcium concentration ([Ca2+]i) oscillations similar to those evoked by sperm, mimic… (More)
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Review
2002
Review
2002
A centrally important factor in initiating egg activation at fertilization is a rise in free Ca(2+) in the egg cytosol. In… (More)
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1998
1998
Microinjection of a truncated form of the c-kit tyrosine kinase present in mouse spermatozoa (tr-kit) activates mouse eggs… (More)
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Highly Cited
1997
Highly Cited
1997
A truncated form of the c-kit tyrosine kinase receptor, corresponding to the phosphotransferase portion of the cytoplasmic… (More)
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1994
1994
Sperm-induced activation of mammalian eggs is associated with a transient increase in the concentration of intracellular Ca2… (More)
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