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duryne

National Institutes of Health

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Polyacetylenes

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2008
2008
Total synthesis of (+)- and (-)-duryne: a potent anticancer agent from the marine sponge Cribrochalina dura. Establishment of the central double bond geometry and the absolute configuration of the…
Duryne is a C30 polyacetylenic alcohol with C2 symmetry. Despite its potent cytotoxicity, its central double bond geometry and… 
2000
2000
Two new acetylenic derivatives and a new meroditerpenoid from a Taiwanese marine sponge Strongylophora durissima.
Further chemical examination of the sponge Strongylophora durissima yielded two new acetylenic derivatives, durissimols A (1) and… 
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