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drug distribution

Known as: distribution drug, distribution drugs 
 
National Institutes of Health

Papers overview

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2016
2016
Drug Distribution. Part 1. Models to Predict Membrane Partitioning
PurposeTissue partitioning is an important component of drug distribution and half-life. Protein binding and lipid partitioning… Expand
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2016
2016
Cryo-sectioning of mice for whole-body imaging of drugs and metabolites with desorption electrospray ionization mass spectrometry imaging - a simplified approach.
A method is presented for whole-body imaging of drugs and metabolites in mice with desorption electrospray ionization mass… Expand
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2016
2016
Liquid Chromatography with Tandem Mass Spectrometry: A Sensitive Method for the Determination of Dehydrodiisoeugenol in Rat Cerebral Nuclei
A new liquid chromatography-tandem mass spectrometry (LC-MS/MS) method is developed for the quantification of dehydrodiisoeugenol… Expand
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2016
2016
Small molecule distribution in rat lung: a comparison of various cryoprotectants as inflation media and their applicability to MSI
Given the recent explosion of mass spectrometric imaging (MSI), it has become easier to assess drug tissue localisation without… Expand
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Review
2015
Review
2015
Anti-angiogenesis or pro-angiogenesis for cancer treatment: focus on drug distribution.
Enhancing chemotherapy delivery to tumors, improving tumor growth control, reducing metastasis, and increasing survival are all… Expand
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2015
2015
Influence of the proton pump inhibitor lansoprazole on distribution and activity of doxorubicin in solid tumors
Cellular causes of resistance and limited drug distribution within solid tumors limit therapeutic efficacy of anticancer drugs… Expand
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2015
2015
Spatial distribution of soluble insulin in pig subcutaneous tissue: Effect of needle length, injection speed and injected volume.
The spatial distribution of a soluble insulin formulation was visualized and quantified in 3-dimensions using X-ray computed… Expand
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2015
2015
Characterization of the comparative drug binding to intra- (liver fatty acid binding protein) and extra- (human serum albumin) cellular proteins.
1. This study compared the extent, affinity, and kinetics of drug binding to human serum albumin (HSA) and liver fatty acid… Expand
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2014
2014
Computational modeling of drug distribution in the posterior segment of the eye: effects of device variables and positions.
A computational model was developed to simulate drug distribution in the posterior segment of the eye after intravitreal… Expand
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Review
2013
Review
2013
The Tumor Microenvironment and Strategies to Improve Drug Distribution
The microenvironment within tumors is composed of a heterogeneous mixture of cells with varying levels of nutrients and oxygen… Expand
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