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double-strand break repair via classical nonhomologous end joining

Known as: C-NHEJ, canonical nonhomologous end joining 
An instance of double-strand break repair via nonhomologous end joining that requires a number of factors important for V(D)J recombination… 
National Institutes of Health

Papers overview

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2020
2020
Making ends meet in class switch recombination
Liu et al. revealed that ERCC6L2 is a DNA double strand break repair factor that both enhances the efficiency of immunoglobulin… 
2019
2019
Class switch recombination junctions are not affected by the absence of the immunoglobulin heavy chain Eμ enhancer
2018
2018
High-throughput sequencing reveals similar molecular signatures for class switch recombination junctions for the γ and α isotypes
2017
2017
Contribution of canonical nonhomologous end joining to chromosomal rearrangements is enhanced by ATM kinase deficiency
Significance Chromosomal rearrangements, such as large deletions, can cause loss of tumor suppressor genes. Rearrangements can be… 
2017
2017
The contribution of DNA DSB repair pathways to the repair of chromosome breaks throughout the cell cycle
Ionizing radiation (IR) induced DNA double strand breaks (DSBs) pose a major threat to cellular homeostasis, as unrepaired or… 
2017
2017
Abstract 2478: PARP trapping by PARP inhibitors have distinct effects on HR and ALT NHEJ DSB repair, potentially impacting its therapeutic efficacy in breast cancers
PARP inhibitors (PARPi) have exhibited clinical success in inherited breast cancers with mutations in homologous recombination… 
2016
2016
DNA Repair Profiling Reve als Nonrandom Outcomes at Cas 9-Mediated Breaks Graphical Abstract Highlights
2015
2015
BP 1 promotes microhomology-mediated end-joining in G 1-phase cells
Alternative non-homologous end joining (alt-NHEJ) was originally identified as a backup repair mechanism in the absence of… 
2014
2014
A role for XLF in DNA repair and recombination in human somatic cells.
2014
2014
The RAG2 C terminus participates in repair pathway choice in vivo and suppresses lymphomagenesis
THE RAG2 C TERMINUS PARTICIPATES IN REPAIR PATHWAY CHOICE IN VIVO AND SUPPRESSES LYMPHOMAGENESIS Vered Gigi Dr. David B Roth DNA… 
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