doramapimod
National Institutes of Health
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Background: Inflammatory cytokines secreted in the bone marrow microenvironment play important roles in modulating cell survival…
Doramapimod,the TNF-α inhibitor,was synthesized via 3 steps from 4-nitro-1-naphthol.The total yield is 31.1%.The 1H-NMR and FAB…
The p38 mitogen-activated protein (MAP) kinases are a family of serine/threonine protein kinases that play important roles in…