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diphosphoryl lipid A

Known as: lipid A DP 
National Institutes of Health

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Broader (1)

Lipid A
analogs & derivatives

Papers overview

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2019
2019
Cell‐line‐based assay for the toxicity/benefit analysis of lipopolysaccharides in plants
There are many immune‐boosting medicinal plants that can potently activate innate immune cells. Recent studies indicate that the… 
2001
2001
Endotoxic Lipid A Interaction with Human Platelets
We previously reported that human blood platelets are directly stimulated by endotoxic Lipid A via the protein kinase C pathway… 
1992
1992
Diphosphoryl lipid A protects rats from lethal hyperoxia.
Bacterial endotoxin has been shown to protect rats from lethal hyperoxia. The structure of endotoxin contains diphosphoryl lipid… 
Highly Cited
1991
Highly Cited
1991
Chemical reduction of 3-oxo and unsaturated groups in fatty acids of diphosphoryl lipid A from the lipopolysaccharide of Rhodopseudomonas sphaeroides. Comparison of biological properties before and…
1988
1988
Pulmonary oxygen toxicity in rats: prevention by pyrogenic diphosphoryl lipid A and potentiation by nontoxic monophosphoryl lipid A and lipid X.
Pretreatment with gram-negative bacterial endotoxin protects rats from the lethal intrathoracic edema produced by continuous… 
1987
1987
The adjuvant properties of a nontoxic monophosphoryl lipid A in hyporesponsive and aging mice.
The immunomodulatory action of a nontoxic monophosphoryl lipid A (MPL) and a toxic diphosphoryl lipid A (DPL) fraction derived… 
1987
1987
Substitution of phosphatidylserine by lipid A in the activation of purified rabbit brain protein kinase C
1986
1986
Enhancement of chemiluminescence and phagocytic activities by nontoxic and toxic forms of lipid A.
The effect on the respiratory burst of murine splenic cells after in vitro exposure to nontoxic monophosphoryl lipid A (MPL… 
1975
1975
Properties of the ribose-ring-opened adenine nucleotide, 2,2'(1-(9-adenyl)-1'-(tri-,diphosphoryl-oxymethyl))-dihydroxydiethylether in mitochondrial adenine-nucleotide translocation.
(Adenine-14C) or (gamma-32P)-labelled 2,2'[1-(9-adenyl)-1'-(tri-, diphosphoryl-oxymethyl]-dihydroxydiethylether (rroANP) was… 
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