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dimethylglycine N-methyltransferase activity

Known as: ApDMT, S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase activity 
Catalysis of the reaction: S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine. [EC:2.1.1.157]
National Institutes of Health

Papers overview

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2010
2010
Effect of N,N-dimethylglycine supplementation in parturition feed for sows on metabolism, nutrient digestibility and reproductive performance.
The current pilot study assessed the influence of N,N-dimethylglycine (DMG) on insulin sensitivity, glucose and fat metabolism… 
2009
2009
Effect of N,N-dimethylglycine supplementation in n-3 polyunsaturated fatty acid rich parturition feed on apparent fecal digestibility, glucosse tolerance and reproductive parameters in sows
Highly Cited
2009
Highly Cited
2009
One carbon metabolism disturbances and the C677T MTHFR gene polymorphism in children with autism spectrum disorders
Autism spectrum disorders (ASDs), which include the prototypic autistic disorder (AD), Asperger’s syndrome (AS) and pervasive… 
2005
2005
Guanine and Plasmid DNA binding of Mono‐ and Trinuclear fac‐[Re(CO)3]+ Complexes with Amino Acid Ligands
We have synthesized and fully characterized four new complexes comprising the fac‐[Re(CO)3]+ moiety and the ligands NH3, L… 
Highly Cited
2002
Highly Cited
2002
Betaine supplementation decreases post-methionine hyperhomocysteinemia in chronic renal failure.
BACKGROUND Fasting and post-methionine load hyperhomocysteinemia are independent risk factors for vascular disease that are… 
Highly Cited
1998
Highly Cited
1998
Simple method for the routine determination of betaine and N,N-dimethylglycine in blood and urine.
A simple and convenient method using commercially available derivatization reagents is described for the measurement of betaine… 
Highly Cited
1993
Highly Cited
1993
Serum betaine, N,N-dimethylglycine and N-methylglycine levels in patients with cobalamin and folate deficiency and related inborn errors of metabolism.
1989
1989
Effects of N,N-dimethylglycine on cardiorespiratory function and lactate production in thoroughbred horses performing incremental treadmill exercise
In a crossover study, either a placebo paste or N,N-dimethylglycine was administered orally at a dose rate of 1.2 mg/kg twice… 
1985
1985
16 THE EFFECT OF NINI DIMETHYLGLYCINE INGESTION UPON AEROBIC PERFORMANCE
Highly Cited
1981
Highly Cited
1981
Formation of N,N-Dimethylglycine, Acetic Acid, and Butyric Acid from Betaine by Eubacterium limosum
Two bacterial strains that grow anaerobically on betaine were isolated from enrichment cultures and identified as strains of… 
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