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dihydrofolate synthase activity

Known as: 7,8-dihydropteroate:L-glutamate ligase (ADP-forming), FHFS activity, dihydrofolate synthetase activity 
Catalysis of the reaction: ATP + dihydropterate + L-glutamate = ADP + phosphate + dihydrofolate. [EC:6.3.2.12]
National Institutes of Health

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dihydrofolate biosynthetic process

Papers overview

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1995
1995
A cluster of four genes encoding enzymes for five steps in the folate biosynthetic pathway of Streptococcus pneumoniae
Two genes, sulB and sulC, in a folate biosynthetic gene cluster of Streptococcus pneumoniae were identified after determination… 
1991
1991
Mutagenesis of the folC gene encoding folylpolyglutamate synthetase-dihydrofolate synthetase in Escherichia coli.
1983
1983
Folylpoly-gamma-glutamate synthetases: properties and regulation.
The substrate specificities of folylpolyglutamate synthetases from Corynebacterium species, Lactobacillus casei, Streptococcus… 
1980
1980
A simple radioassay for dihydrofolate synthetase activity in Escherichia coli and its application to an inhibition study of new pteroate analogs.
  • R. Ho
  • 1980
  • Corpus ID: 35451466
1980
1980
A simple radioassay for dihydrofolate synthetase activity in Escherichia coli and its application to an inhibition study of new pteroate analogs.
1980
1980
Intracellular distribution, purification, and properties of dihydrofolate synthetase from pea seedlings.
1977
1977
Nutritional requirements for folate compounds and some enzyme activities involved in the folate biosynthesis.
Dihydrofolate synthetase activity is widely distributed in various microorganisms and mushrooms. Animals and microorganisms i.e… 
1972
1972
The hepatic activities of 1-carbon enzymes during the chronic administration of diethylnitrosamine, 2-acetylaminofluorene, and n,n-dimethyl-4-aminoazobenzene to rats.
Summary The levels of seven enzymes involved in the metabolism of 1-carbon compounds and their precursors were investigated in… 
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