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dihydrobiopterin metabolic process

Known as: dihydropterin metabolic process, dihydropterin metabolism 
The chemical reactions and pathways involving a dihydrobiopterin, a reduced pteridine derivative related to folic acid; it acts as an electron… 
National Institutes of Health

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dihydrobiopterin reduction

Papers overview

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1995
1995
Catalytic characterization of 4a-hydroxytetrahydropterin dehydratase.
The cofactor product of the aromatic amino acid hydroxylases, 4a-hydroxy-6(R)-tetrahydrobiopterin, requires dehydration before… 
1994
1994
Cytotoxicity of 6-biopterin to human melanocytes.
(6R)5,6,7,8 tetrahydrobiopterin (6-BH4) is an important cofactor in the regulation of melanogenesis in melanocytes, where it… 
Highly Cited
1993
Highly Cited
1993
Mutation in the 4a-carbinolamine dehydratase gene leads to mild hyperphenylalaninemia with defective cofactor metabolism.
Hyperphenylalaninemias represent a major class of inherited metabolic disorders. They are most often caused by mutations in the… 
Highly Cited
1990
Highly Cited
1990
Interaction of sulfonamide and sulfone compounds with Toxoplasma gondii dihydropteroate synthase.
Toxoplasma gondii is a common protozoan disease that often causes life-threatening disease, particularly among patients with the… 
Highly Cited
1988
Highly Cited
1988
The auto-oxidation of tetrahydrobiopterin.
The product of the aerobic oxidation of tetrahydrobiopterin, quinonoid dihydrobiopterin, is unstable and rapidly rearranges to… 
1984
1984
Stoichiometric reduction of phenylalanine hydroxylase by its cofactor: a requirement for enzymatic activity.
We have found that rat liver phenylalanine hydroxylase oxidizes a stoichiometric amount of its cofactor, 6-methyl-5,6,7,8… 
1983
1983
6,6-Dimethylpterins: stable quinoid dihydropterin substrate for dihydropteridine reductase and tetrahydropterin cofactor for phenylalanine hydroxylase.
The tautomeric structure of the cofactor product of aromatic amino acid hydroxylases, quinoid dihydrobiopterin, is still unknown… 
Highly Cited
1978
Highly Cited
1978
Regional and subcellular distribution and some factors in the regulation of reduced pterins in rat brain.
We have studied the regional and subcellular distribution, functional role, and pharmacology of quinoid dihydropterin reductase… 
1973
1973
Properties of purifed quinonoid dihydropterin reductase.
Quinonoid dihydropterin reductase has been purified to homogeneity from sheep liver, sheep brain, and beef adrenal medulla. Each… 
1972
1972
Mechanism of oxidation of tetrahydropterins.
The oxidation of tetrahydropterins and 7,8-dihydropterins by ferric iron has been examined by both polarographic and spectral… 
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