dihydrexidine

Known as: 10,11-dihydroxyhexahydrobenzo(a)phenanthridine, Benzo(a)phenanthridine-10,11-diol, 5,6,6a,7,8,12b-hexahydro-, trans- 
 
National Institutes of Health

Papers overview

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2015
2015
Pharmacological enhancement of prefrontal D1 dopamine receptor function remains a promising therapeutic approach to ameliorate… (More)
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Highly Cited
2002
Highly Cited
2002
Prefrontal cortical dopamine (DA) modulates pyramidal cell excitability directly and indirectly by way of its actions on local… (More)
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2002
2002
D(2)-like dopamine receptors mediate functional changes via activation of inhibitory G proteins, including those that affect… (More)
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Highly Cited
2000
Highly Cited
2000
The effects of dopamine (DA) on a persistent Na(+) current (I(NaP)) in layer V-VI prefrontal cortical (PFC) pyramidal cells were… (More)
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1998
1998
The contribution of dopamine D1 receptor stimulation to the motor effects of dopaminergic drugs in patients with Parkinson's… (More)
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1997
1997
Dihydrexidine is a selective, full-efficacy dopamine D1 receptor agonist that has displayed therapeutic potential in Parkinson's… (More)
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Highly Cited
1996
Highly Cited
1996
The role of the mesolimbic dopaminergic system in the reinforcement of learning suggests that dopamine should be able to modulate… (More)
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Highly Cited
1994
Highly Cited
1994
Dopamine (DA) D1 receptor compounds were examined in monkeys for effects on the working memory functions of the prefrontal cortex… (More)
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1993
1993
Although partial efficacy dopamine D1 receptor agonists have little therapeutic benefit in parkinsonism, the first high potency… (More)
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1991
1991
Dihydrexidine (trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phena nthridine) was reported recently to be the first full… (More)
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