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dideoxypetrosynol A

National Institutes of Health

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2 relations

Broader (2)

Fatty AlcoholsPolyacetylenes

Papers overview

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2008
2008
First Total Synthesis of the Potent Anticancer Natural Product Dideoxypetrosynol A: Preparation of the "Skipped" (Z)-Enediyne Moiety by Oxidative Coupling of Homopropargyl Phosphonium Ylide.
Dideoxypetrosynol A is a C30 polyacetylenic alcohol with C2 symmetry. The first total synthesis of both enantiomers of the potent… 
2006
2006
Suppression of U937 human monocytic leukemia cell growth by dideoxypetrosynol A, a polyacetylene from the sponge Petrosia sp., via induction of Cdk inhibitor p16 and down-regulation of pRB…
Dideoxypetrosynol A, a polyacetylene from the marine sponge Petrosia sp., is known to exhibit significant selective cytotoxic… 
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