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diacylglycerol O-acyltransferase activity
Known as:
1,2-diacylglycerol acyltransferase activity
, diglyceride O-acyltransferase activity
, diacylglycerol acyltransferase activity
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Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol. [EC:2.3.1.20]
National Institutes of Health
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Papers overview
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Highly Cited
2010
Highly Cited
2010
A distinct DGAT with sn-3 acetyltransferase activity that synthesizes unusual, reduced-viscosity oils in Euonymus and transgenic seeds
T. Durrett
,
Daniel D Mcclosky
,
A. W. Tumaney
,
Dezi A. Elzinga
,
J. Ohlrogge
,
M. Pollard
Proceedings of the National Academy of Sciences…
2010
Corpus ID: 3045085
Endosperm and embryo tissues from the seeds of Euonymus alatus (Burning Bush) accumulate high levels of 3-acetyl-1,2-diacyl-sn…
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2005
2005
Increased diacylglycerol acyltransferase activity is associated with triglyceride accumulation in tissues of diet-induced insulin-resistant hyperlipidemic hamsters.
A. Casaschi
,
Geoffrey K. Maiyoh
,
K. Adeli
,
A. Theriault
Metabolism: Clinical and Experimental
2005
Corpus ID: 40853054
Highly Cited
2003
Highly Cited
2003
Cellular aspects of intestinal lipoprotein assembly in Psammomys obesus: a model of insulin resistance and type 2 diabetes.
M. Zoltowska
,
E. Ziv
,
+5 authors
E. Levy
Diabetes
2003
Corpus ID: 17389977
Although postprandial hypertriglyceridemia is a major contributing factor in the development of atherosclerosis, little…
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Highly Cited
2002
Highly Cited
2002
Intestinal apolipoprotein B secretion is inhibited by the flavonoid quercetin: Potential role of microsomal triglyceride transfer protein and diacylglycerol acyltransferase
A. Casaschi
,
Qi Wang
,
Ka'ohimanu Dang
,
Alison Richards
,
A. Theriault
Lipids
2002
Corpus ID: 4003847
Recent studies have yielded evidence that plant flavonoids reduce hepatic lipid and apolipoprotein B (apoB) secretion. However…
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Highly Cited
1997
Highly Cited
1997
Triacylglycerols are synthesised and utilized by transacylation reactions in microsomal preparations of developing safflower (Carthamus tinctorius L.) seeds
K. Stobart
,
M. Mancha
,
M. Lenman
,
A. Dahlqvist
,
S. Stymne
Planta
1997
Corpus ID: 20540672
Abstract. Microsomal membrane preparations from the immature cotyledons of safflower (Carthamus tinctorius) catalysed the…
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Highly Cited
1992
Highly Cited
1992
Serum lipids, hepatic glycerolipid metabolism and peroxisomal fatty acid oxidation in rats fed omega-3 and omega-6 fatty acids.
A. C. Rustan
,
E. Christiansen
,
C. Drevon
Biochemical Journal
1992
Corpus ID: 24014964
Rats were fed, for 3 weeks, high-fat (20% w/w) diets containing sunflower-seed oil, linseed oil or fish oil. Chow-fed rats were…
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Highly Cited
1990
Highly Cited
1990
The assembly and secretion of apoB 100 containing lipoproteins in Hep G2 cells. Evidence for different sites for protein synthesis and lipoprotein assembly.
J. Borén
,
M. Wettesten
,
+4 authors
S. Olofsson
Journal of Biological Chemistry
1990
Corpus ID: 22762602
Highly Cited
1981
Highly Cited
1981
Regulation of triacylglycerol synthesis in the liver: a decrease in diacylglycerol acyltransferase activity after treatment of isolated rat hepatocytes with glucagon.
H. Haagsman
,
C. D. Haas
,
Math J.H. Geelen
,
L.M.G. Van Golde
Biochimica et Biophysica Acta
1981
Corpus ID: 6782835
Highly Cited
1976
Highly Cited
1976
Triacylglycerol synthesis in isolated fat cells. Studies on the microsomal diacylglycerol acyltransferase activity using ethanol-dispersed diacylglycerols.
R. Coleman
,
R. Bell
Journal of Biological Chemistry
1976
Corpus ID: 38795488
1976
1976
Acyl specificity in triglyceride synthesis by lactating rat mammary gland.
C. Lin
,
S. Abraham
,
S. Smith
Journal of Lipid Research
1976
Corpus ID: 8387293
We have studied the specificity of the acyl-CoA:diglyceride acyltransferase reaction in lactating rat mammary gland to provide a…
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