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detomidine

 
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
OBJECTIVE To study the analgesic potency of the alpha2-agonist romifidine in the horse using both an electrical current and a… Expand
Highly Cited
2000
Highly Cited
2000
The cardiovascular effects of medetomidine, detomidine, and xylazine in horses were studied. Fifteen horses, whose right carotid… Expand
Highly Cited
2000
Highly Cited
2000
 
Highly Cited
1997
Highly Cited
1997
In the present study, the hypoxaemic potential of four alpha 2 agonists possessing different selectivity for alpha 2… Expand
Highly Cited
1995
Highly Cited
1995
In a double blind study, eight horses were treated intravenously at seven-day intervals with detomidine at doses of 10, 20 and 40… Expand
Highly Cited
1992
Highly Cited
1992
The sedative effects of a new alpha 2-adrenoceptor agonist, romifidine, were compared with those of xylazine and detomidine. Five… Expand
Highly Cited
1991
Highly Cited
1991
The cardiovascular effects of xylazine and detomidine in horses were studied. Six horses were given each of the following 5… Expand
Review
1989
Review
1989
  • R. Virtanen
  • Acta veterinaria Scandinavica. Supplementum
  • 1989
  • Corpus ID: 24222012
Medetomidine, (+/-)-4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole, is a very potent, selective and specific full agonist at both… Expand
Highly Cited
1988
Highly Cited
1988
Medetomidine (4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole) was tested for alpha 2-adrenoceptor agonist activity and compared to… Expand
Highly Cited
1988
Highly Cited
1988
The effects of administration of one of four opiates (pethidine 1 mg/kg bodyweight (bwt), morphine 0.1 mg/kg bwt, methadone 0.1… Expand